ENSMUSG00000029726


Mus musculus

Features
Gene ID: ENSMUSG00000029726
  
Biological name :Mepce
  
Synonyms : 7SK snRNA methylphosphate capping enzyme / Mepce / Q8K3A9
  
Possible biological names infered from orthology : methylphosphate capping enzyme / Q7L2J0
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 137781906
Gene end: 137787655
  
Corresponding Affymetrix probe sets: 10534921 (MoGene1.0st)   1420140_at (Mouse Genome 430 2.0 Array)   1424288_at (Mouse Genome 430 2.0 Array)   1449747_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031740
Ensembl peptide - ENSMUSP00000118688
Ensembl peptide - ENSMUSP00000143201
NCBI entrez gene - 231803     See in Manteia.
MGI - MGI:106477
RefSeq - XM_017320873
RefSeq - NM_144913
RefSeq Peptide - NP_659162
swissprot - A0A0G2JFK0
swissprot - Q8K3A9
swissprot - F6XIE4
Ensembl - ENSMUSG00000029726
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mepceENSDARG00000059461Danio rerio
 MEPCEENSDARG00000035771Danio rerio
 MEPCEENSG00000146834Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010675  RNA methyltransferase bin3, C-terminal
 IPR024160  Bin3-type S-adenosyl-L-methionine binding domain
 IPR025714  Methyltransferase domain
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IGI
 biological_processGO:0001510 RNA methylation IEA
 biological_processGO:0016073 snRNA metabolic process IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0035562 negative regulation of chromatin binding IGI
 biological_processGO:0040031 snRNA modification IEA
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008173 RNA methyltransferase activity IEA
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Memo1tm1b(EUCOMM)Wtsi/Memo1+
Genetic Background: C57BL/6N-Memo1tm1b(EUCOMM)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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