ENSMUSG00000029781


Mus musculus

Features
Gene ID: ENSMUSG00000029781
  
Biological name :Fkbp9
  
Synonyms : Fkbp9 / Peptidyl-prolyl cis-trans isomerase FKBP9 / Q9Z247
  
Possible biological names infered from orthology : FK506 binding protein 9 / O95302
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B3
Gene start: 56832059
Gene end: 56879358
  
Corresponding Affymetrix probe sets: 10538547 (MoGene1.0st)   1423677_at (Mouse Genome 430 2.0 Array)   1437687_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031795
NCBI entrez gene - 27055     See in Manteia.
MGI - MGI:1350921
RefSeq - NM_012056
RefSeq Peptide - NP_036186
swissprot - Q9Z247
Ensembl - ENSMUSG00000029781
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fkbp9ENSDARG00000005023Danio rerio
 FKBP9ENSGALG00000037669Gallus gallus
 FKBP9ENSG00000122642Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fkbp10 / Q61576 / Peptidyl-prolyl cis-trans isomerase FKBP10 / Q96AY3* / FK506 binding protein 10*ENSMUSG0000000155559
Fkbp7 / O54998 / Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 2, mRNA. / Q9Y680* / FK506 binding protein 7*ENSMUSG0000000273212
Fkbp14 / P59024 / Peptidyl-prolyl cis-trans isomerase FKBP14 / Q9NWM8* / FK506 binding protein 14*ENSMUSG0000003807412
Fkbp11 / Q9D1M7 / Peptidyl-prolyl cis-trans isomerase FKBP11 / Q9NYL4* / FK506 binding protein 11*ENSMUSG0000000335512
Fkbp2 / P45878 / Peptidyl-prolyl cis-trans isomerase FKBP2 / P26885* / FK506 binding protein 2*ENSMUSG0000005662911


Protein motifs (from Interpro)
Interpro ID Name
 IPR001179  FKBP-type peptidyl-prolyl cis-trans isomerase domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR023566  Peptidyl-prolyl cis-trans isomerase, FKBP-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006457 protein folding IDA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005528 FK506 binding IBA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002942 decreased circulating alanine transaminase level "decreased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fhl1tm1a(EUCOMM)Wtsi/Fhl1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Fhl1tm1a(EUCOMM)Wtsi/H

 MP:0005567 decreased circulating total protein level "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]
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Allelic Composition: Fhl1tm1a(EUCOMM)Wtsi/Fhl1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Fhl1tm1a(EUCOMM)Wtsi/H

 MP:0005632 decreased circulating aspartate transaminase level "less than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Fhl1tm1a(EUCOMM)Wtsi/Fhl1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Fhl1tm1a(EUCOMM)Wtsi/H

 MP:0005634 decreased circulating sodium level "less than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Fhl1tm1a(EUCOMM)Wtsi/Fhl1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Fhl1tm1a(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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