ENSMUSG00000029790


Mus musculus

Features
Gene ID: ENSMUSG00000029790
  
Biological name :Cep41
  
Synonyms : Centrosomal protein of 41 kDa / Cep41 / Q99NF3
  
Possible biological names infered from orthology : centrosomal protein 41 / Q9BYV8
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: A3.3
Gene start: 30653457
Gene end: 30693749
  
Corresponding Affymetrix probe sets: 10543725 (MoGene1.0st)   1419686_at (Mouse Genome 430 2.0 Array)   1434576_at (Mouse Genome 430 2.0 Array)   1443792_at (Mouse Genome 430 2.0 Array)   1445416_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116240
Ensembl peptide - ENSMUSP00000128707
Ensembl peptide - ENSMUSP00000145510
Ensembl peptide - ENSMUSP00000138696
Ensembl peptide - ENSMUSP00000031810
Ensembl peptide - ENSMUSP00000110783
Ensembl peptide - ENSMUSP00000110784
NCBI entrez gene - 83922     See in Manteia.
MGI - MGI:1891414
RefSeq - XM_006505207
RefSeq - XM_006505209
RefSeq - XM_006505210
RefSeq - XM_006505211
RefSeq - XM_006505213
RefSeq - XM_011241090
RefSeq - NM_031998
RefSeq - XM_006505208
RefSeq Peptide - NP_114387
swissprot - S4R2L7
swissprot - D3Z672
swissprot - H9KUZ8
swissprot - A0A0N4SWG6
swissprot - Q99NF3
swissprot - E9Q8S3
Ensembl - ENSMUSG00000029790
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cep41ENSDARG00000038500Danio rerio
 CEP41ENSGALG00000008103Gallus gallus
 CEP41ENSG00000106477Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001763  Rhodanese-like domain
 IPR036873  Rhodanese-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0018095 protein polyglutamylation ISS
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0060271 cilium assembly ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005814 centriole IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium ISO
 cellular_componentGO:0036064 ciliary basal body ISO
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000288 abnormal pericardium morphology "malformation of the fibroserous membrane covering the heart and beginning of the great vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:54408]
Show

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Kdm8tm1.2Tasu/Kdm8tm1.2Tasu
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C3H * C57BL/6

 MP:0000841 abnormal hindbrain morphology "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]
Show

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Kdm8tm1.2Tasu/Kdm8tm1.2Tasu
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C3H * C57BL/6

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Kdm8tm1.2Tasu/Kdm8tm1.2Tasu
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C3H * C57BL/6

 MP:0001700 abnormal embryo turning "atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Kdm8tm1.2Tasu/Kdm8tm1.2Tasu
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C3H * C57BL/6

 MP:0001915 intracranial hemorrhage "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Kdm8tm1.2Tasu/Kdm8tm1.2Tasu
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C3H * C57BL/6

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Kdm8tm1.2Tasu/Kdm8tm1.2Tasu
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C3H * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr