ENSMUSG00000029848


Mus musculus

Features
Gene ID: ENSMUSG00000029848
  
Biological name :Stra8
  
Synonyms : P70278 / Stimulated by retinoic acid 8 protein / Stra8
  
Possible biological names infered from orthology : Q7Z7C7 / stimulated by retinoic acid 8
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B1
Gene start: 34920163
Gene end: 34939344
  
Corresponding Affymetrix probe sets: 10537231 (MoGene1.0st)   1420568_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031876
Ensembl peptide - ENSMUSP00000110649
Ensembl peptide - ENSMUSP00000110651
Ensembl peptide - ENSMUSP00000139136
NCBI entrez gene - 20899     See in Manteia.
MGI - MGI:107917
RefSeq - XM_006505829
RefSeq - XM_011241270
RefSeq - NM_009292
RefSeq Peptide - NP_033318
swissprot - P70278
swissprot - F2Z435
swissprot - V9GXG4
Ensembl - ENSMUSG00000029848
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STRA8ENSGALG00000011722Gallus gallus
 STRA8ENSG00000146857Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR033537  Stimulated by retinoic acid gene 8 protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048133 male germ-line stem cell asymmetric division IMP
 biological_processGO:0048477 oogenesis IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0071300 cellular response to retinoic acid IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001132 absent mature ovarian follicles "failure of ovarian follicle differentiation" [J:35782]
Show

Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nanos2tm1Ysa/Nanos2tm1Ysa,Stra8tm1Ysa/Stra8tm1Ysa
Genetic Background: involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)

Allelic Composition: Nanos2tm1Ysa/Nanos2tm1Ysa,Stra8tm1Ysa/Stra8+
Genetic Background: involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)

 MP:0004805 absent oocytes "absence of mature germ cells in the female" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: C57BL/6-Ins2Akita/J

Allelic Composition: Stra8tm1Ysa/Stra8tm1Ysa
Genetic Background: involves: C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

Allelic Composition: Nanos2tm1Ysa/Nanos2tm1Ysa,Stra8tm1Ysa/Stra8tm1Ysa
Genetic Background: involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)

Allelic Composition: Nanos2tm1Ysa/Nanos2tm1Ysa,Stra8tm1Ysa/Stra8+
Genetic Background: involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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