ENSMUSG00000029909


Mus musculus

Features
Gene ID: ENSMUSG00000029909
  
Biological name :Prss37
  
Synonyms : Probable inactive serine protease 37 / Prss37 / Q9DAA4
  
Possible biological names infered from orthology : A4D1T9 / serine protease 37
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: B1
Gene start: 40514824
Gene end: 40519508
  
Corresponding Affymetrix probe sets: 10544263 (MoGene1.0st)   1442795_x_at (Mouse Genome 430 2.0 Array)   1449427_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031967
NCBI entrez gene - 67690     See in Manteia.
MGI - MGI:1914940
RefSeq - NM_026317
RefSeq - XM_006506525
RefSeq Peptide - NP_080593
swissprot - Q9DAA4
Ensembl - ENSMUSG00000029909
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A4D1T9ENSG00000165076Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Prss58 / Q8BW11 / Putative inactive serine protease 58 / Q8IYP2* / serine protease 58*ENSMUSG0000005193628
1700074P13Rik / RIKEN cDNA 1700074P13 geneENSMUSG0000002988327


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR009003  Peptidase S1, PA clan


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0007339 binding of sperm to zona pellucida IMP
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0051604 protein maturation IMP
 biological_processGO:0070613 regulation of protein processing IEA
 biological_processGO:1905516 positive regulation of fertilization IMP
 biological_processGO:2000344 positive regulation of acrosome reaction IEA
 cellular_componentGO:0001669 acrosomal vesicle ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Prkcitm1.1Rfar/Prkcitm1.1Rfar
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * NMRI

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Prkcitm1.1Rfar/Prkcitm1.1Rfar
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * NMRI

 MP:0001932 abnormal spermiogenesis "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prkcitm1.1Rfar/Prkcitm1.1Rfar
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * NMRI

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prkcitm1.1Rfar/Prkcitm1.1Rfar
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * NMRI

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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