ENSMUSG00000030041


Mus musculus

Features
Gene ID: ENSMUSG00000030041
  
Biological name :M1ap
  
Synonyms : M1ap / Meiosis 1 arrest protein / Q9Z0E1
  
Possible biological names infered from orthology : meiosis 1 associated protein / Q8TC57
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: C3
Gene start: 82946902
Gene end: 83030309
  
Corresponding Affymetrix probe sets: 10539251 (MoGene1.0st)   1449358_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109613
Ensembl peptide - ENSMUSP00000144948
NCBI entrez gene - 110958     See in Manteia.
MGI - MGI:1315200
RefSeq - XM_011241141
RefSeq - NM_033079
RefSeq - XM_006505368
RefSeq Peptide - NP_149070
swissprot - Q9Z0E1
swissprot - A0A0N4SV45
Ensembl - ENSMUSG00000030041
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 m1apENSDARG00000099485Danio rerio
 M1APENSG00000159374Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR033587  Meiosis 1 arrest protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing NAS
 biological_processGO:0007127 meiosis I IEA
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0007292 female gamete generation IEP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031497 chromatin assembly NAS
 biological_processGO:0051308 male meiosis chromosome separation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0002686 globozoospermia "malformation of the acrosome resulting in a round sperm head" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0006362 abnormal male germ cell morphology "any structural anomaly of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0010948 abnormal double-strand DNA break repair "any annomaly in the process of repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix" [GO:0006302]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

 MP:0011751 abnormal X-Y chromosome synapsis during male meiosis "an anomaly in the process in which the side by side pairing and physical juxtaposition of X and Y chromosomes is created at the metaphase plate, usually resulting in incorrect sex chromosome disjunction" [MGI:llw2]
Show

Allelic Composition: Krt10tm2Tmm/Krt10tm2Tmm
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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