ENSMUSG00000030172


Mus musculus

Features
Gene ID: ENSMUSG00000030172
  
Biological name :Erc1
  
Synonyms : ELKS/Rab6-interacting/CAST family member 1 / Erc1 / Q99MI1
  
Possible biological names infered from orthology : Q8IUD2
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: F1
Gene start: 119570796
Gene end: 119848167
  
Corresponding Affymetrix probe sets: 10547404 (MoGene1.0st)   10547408 (MoGene1.0st)   10547410 (MoGene1.0st)   1421501_a_at (Mouse Genome 430 2.0 Array)   1424247_at (Mouse Genome 430 2.0 Array)   1441493_at (Mouse Genome 430 2.0 Array)   1451279_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139256
Ensembl peptide - ENSMUSP00000032279
Ensembl peptide - ENSMUSP00000078534
Ensembl peptide - ENSMUSP00000138823
Ensembl peptide - ENSMUSP00000138989
Ensembl peptide - ENSMUSP00000139030
Ensembl peptide - ENSMUSP00000139031
Ensembl peptide - ENSMUSP00000139118
Ensembl peptide - ENSMUSP00000139152
Ensembl peptide - ENSMUSP00000139207
NCBI entrez gene - 111173     See in Manteia.
MGI - MGI:2151013
RefSeq - XM_017321332
RefSeq - NM_053204
RefSeq - NM_178085
RefSeq - XM_006505370
RefSeq - XM_006505371
RefSeq - XM_006505373
RefSeq - XM_006505378
RefSeq - XM_011241143
RefSeq - XM_017321328
RefSeq - XM_017321329
RefSeq - XM_017321330
RefSeq - XM_017321331
RefSeq Peptide - NP_835186
RefSeq Peptide - NP_444434
swissprot - V9GWT6
swissprot - V9GX53
swissprot - V9GXF0
swissprot - V9GXH3
swissprot - V9GXL1
swissprot - F8VPM7
swissprot - V9GXP8
swissprot - Q99MI1
Ensembl - ENSMUSG00000030172
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ERC1ENSDARG00000076014Danio rerio
 erc1aENSDARG00000009941Danio rerio
 erc1bENSDARG00000031930Danio rerio
 ERC1ENSGALG00000012994Gallus gallus
 ERC1ENSG00000082805Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Erc2 / Q6PH08 / Mus musculus ELKS/RAB6-interacting/CAST family member 2 (Erc2), transcript variant 2, mRNA. / O15083* / ELKS/RAB6-interacting/CAST family member 2*ENSMUSG0000004064061


Protein motifs (from Interpro)
Interpro ID Name
 IPR019018  Rab-binding domain FIP-RBD
 IPR019323  Active zone protein ELKS
 IPR037245  FIP-RBD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007252 I-kappaB phosphorylation ISO
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0008385 IkappaB kinase complex ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0045202 synapse IDA
 cellular_componentGO:0048786 presynaptic active zone IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IDA
 molecular_functionGO:0030165 PDZ domain binding ISS
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: X/SryCB
Genetic Background: C57BL/6JEi-Chr YCB/EiJ

 MP:0003992 increased mortality induced by ionizing radiation "greater sensitivity to doses of ionizing radiation that include ultraviolet light, X-rays, or gamma rays" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Hand1tm1.1(EGFP/cre)Abfi/Hand1+
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor

 MP:0008762 embryonic lethality "death of an animal in the embryonic period (Mus: up to E14)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hand1tm1.1(EGFP/cre)Abfi/Hand1+
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: X/SryCB
Genetic Background: C57BL/6JEi-Chr YCB/EiJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr