ENSMUSG00000030428


Mus musculus

Features
Gene ID: ENSMUSG00000030428
  
Biological name :Ttyh1
  
Synonyms : Q9D3A9 / Ttyh1 / tweety family member 1
  
Possible biological names infered from orthology : Q9H313
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A1
Gene start: 4119408
Gene end: 4136708
  
Corresponding Affymetrix probe sets: 10549594 (MoGene1.0st)   1422694_at (Mouse Genome 430 2.0 Array)   1422695_at (Mouse Genome 430 2.0 Array)   1422696_at (Mouse Genome 430 2.0 Array)   1426617_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146131
Ensembl peptide - ENSMUSP00000115623
Ensembl peptide - ENSMUSP00000120182
Ensembl peptide - ENSMUSP00000032594
Ensembl peptide - ENSMUSP00000146170
Ensembl peptide - ENSMUSP00000078384
Ensembl peptide - ENSMUSP00000113937
NCBI entrez gene - 57776     See in Manteia.
MGI - MGI:1889007
RefSeq - NM_021324
RefSeq - NM_001001454
RefSeq - NM_001109765
RefSeq - NM_001305822
RefSeq Peptide - NP_001001454
RefSeq Peptide - NP_067299
RefSeq Peptide - NP_001292751
RefSeq Peptide - NP_001103235
swissprot - Q9D3A9
swissprot - A0A0U1RPU8
swissprot - A0A0U1RPY1
swissprot - D6RG66
swissprot - G8JL37
Ensembl - ENSMUSG00000030428
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttyh1ENSDARG00000076804Danio rerio
 TTYH1ENSG00000167614Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ttyh2 / Q3TH73 / tweety family member 2 / Q9BSA4*ENSMUSG0000003471440
Ttyh3 / Q6P5F7 / tweety family member 3 / Q9C0H2*ENSMUSG0000003656537


Protein motifs (from Interpro)
Interpro ID Name
 IPR006990  Tweety


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0031589 cell-substrate adhesion IDA
 biological_processGO:0046847 filopodium assembly IDA
 biological_processGO:0098609 cell-cell adhesion IDA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030868 smooth endoplasmic reticulum membrane IDA
 cellular_componentGO:0031527 filopodium membrane IDA
 cellular_componentGO:0032433 filopodium tip IDA
 cellular_componentGO:0034707 chloride channel complex IEA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0072320 volume-sensitive chloride channel activity IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Hbegftm2Mek/Hbegftm2Mek
Genetic Background: B6.Cg-Hbegftm2Mek

 MP:0003111 abnormal nucleus morphology "abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Hbegftm2Mek/Hbegftm2Mek
Genetic Background: B6.Cg-Hbegftm2Mek

 MP:0003707 increased nucleus count "greater than one nuclei present per cell body when one is expected; often due to failed cytokinesis" [pg:Philip Groth submission]
Show

Allelic Composition: Hbegftm2Mek/Hbegftm2Mek
Genetic Background: B6.Cg-Hbegftm2Mek

 MP:0004046 abnormal mitosis "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Hbegftm2Mek/Hbegftm2Mek
Genetic Background: B6.Cg-Hbegftm2Mek

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Hbegftm2Mek/Hbegftm2Mek
Genetic Background: B6.Cg-Hbegftm2Mek

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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