ENSMUSG00000030659


Mus musculus

Features
Gene ID: ENSMUSG00000030659
  
Biological name :Nucb2
  
Synonyms : Nucb2 / nucleobindin 2 / P81117
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F1
Gene start: 116504369
Gene end: 116540584
  
Corresponding Affymetrix probe sets: 10556583 (MoGene1.0st)   1418355_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032895
Ensembl peptide - ENSMUSP00000138741
Ensembl peptide - ENSMUSP00000138757
NCBI entrez gene - 53322     See in Manteia.
MGI - MGI:1858179
RefSeq - XM_006508028
RefSeq - NM_001130479
RefSeq - XM_006508024
RefSeq - XM_006508025
RefSeq - XM_006508026
RefSeq - XM_006508027
RefSeq Peptide - NP_001123951
swissprot - P81117
swissprot - Q3UKN6
swissprot - S4R2R9
Ensembl - ENSMUSG00000030659
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nucb2aENSDARG00000036299Danio rerio
 nucb2bENSDARG00000036291Danio rerio
 NUCB2ENSGALG00000006147Gallus gallus
 NUCB2ENSG00000070081Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nucb1 / Q02819 / Nucleobindin-1 / Q02818*ENSMUSG0000003082459


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR028813  Nucleobindin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006874 cellular calcium ion homeostasis TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005640 nuclear outer membrane IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment ISO
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Slc12a6Gt(OST458419)Lex/Slc12a6Gt(OST458419)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0005333 decreased heart rate "fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]
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Allelic Composition: Slc12a6Gt(OST458419)Lex/Slc12a6Gt(OST458419)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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