ENSMUSG00000030717


Mus musculus

Features
Gene ID: ENSMUSG00000030717
  
Biological name :Nupr1
  
Synonyms : Nuclear protein 1 / Nupr1 / Q9WTK0
  
Possible biological names infered from orthology : nuclear protein 1, transcriptional regulator / O60356
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F3
Gene start: 126623249
Gene end: 126630861
  
Corresponding Affymetrix probe sets: 10567995 (MoGene1.0st)   1419665_a_at (Mouse Genome 430 2.0 Array)   1419666_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032961
Ensembl peptide - ENSMUSP00000145914
Ensembl peptide - ENSMUSP00000139489
NCBI entrez gene - 56312     See in Manteia.
MGI - MGI:1891834
RefSeq - NM_019738
RefSeq Peptide - NP_062712
swissprot - A0A0U1RPB6
swissprot - A0A087WNT8
swissprot - Q9WTK0
Ensembl - ENSMUSG00000030717
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nupr1ENSDARG00000094557Danio rerio
 NUPR1ENSG00000176046Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018792  Nuclear protein 1-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002526 acute inflammatory response IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006473 protein acetylation IMP
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0009636 response to toxic substance IMP
 biological_processGO:0031401 positive regulation of protein modification process IMP
 biological_processGO:0035914 skeletal muscle cell differentiation IMP
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0045786 negative regulation of cell cycle IMP
 biological_processGO:0048147 negative regulation of fibroblast proliferation IMP
 biological_processGO:2000194 regulation of female gonad development IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032993 protein-DNA complex IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003682 chromatin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000313 abnormal cell death "anomalous cessation of function at the cellular level" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001938 delayed sexual maturation "immaturity of the sexual organs at a given age" [J:61190]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002679 abnormal corpora lutea "malformed or absent yellow endocrine body formed in the ovary after follicle rupture" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003077 abnormal cell cycle "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005131 increased follicle stimulating hormone level "greater than expected concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005132 decreased luteinizing hormone level "lower than normal concentration of LH " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005133 increased luteinizing hormone level "higher than normal levels of LH " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011703 increased fibroblast proliferation "greater the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
Show

Allelic Composition: F2rl1tm1Mslb/F2rl1tm1Mslb
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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