ENSMUSG00000031166


Mus musculus

Features
Gene ID: ENSMUSG00000031166
  
Biological name :Wdr13
  
Synonyms : Q91V09 / Wdr13 / WD repeat domain 13
  
Possible biological names infered from orthology : Q9H1Z4
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A1.1
Gene start: 8123301
Gene end: 8132892
  
Corresponding Affymetrix probe sets: 10603453 (MoGene1.0st)   1425490_a_at (Mouse Genome 430 2.0 Array)   1451728_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138509
Ensembl peptide - ENSMUSP00000138392
Ensembl peptide - ENSMUSP00000138468
Ensembl peptide - ENSMUSP00000033506
Ensembl peptide - ENSMUSP00000111286
Ensembl peptide - ENSMUSP00000120395
NCBI entrez gene - 73447     See in Manteia.
MGI - MGI:1914661
RefSeq - XM_006527703
RefSeq - NM_001290783
RefSeq - NM_026137
RefSeq - NM_028542
RefSeq Peptide - NP_001277712
RefSeq Peptide - NP_080413
RefSeq Peptide - NP_082818
swissprot - Q32P16
swissprot - Q91V09
swissprot - S4R225
swissprot - S4R258
swissprot - A2AC24
Ensembl - ENSMUSG00000031166
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdr13ENSDARG00000022974Danio rerio
 WDR13ENSG00000101940Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:1904691 negative regulation of type B pancreatic cell proliferation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005815 microtubule organizing center ISO
 cellular_componentGO:0005886 plasma membrane ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:1990841 promoter-specific chromatin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Vcantm2Hwat/Vcantm2Hwat
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0005491 islet cell hyperplasia "increased numbers cells within the structures that are scattered throughout the pancreas and comprise its endocrine portion" [J:48446, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0005658 susceptibility to diet-induced obesity "more likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0009108 increased pancreas weight "increase in the average weight of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [MESH:A03.734, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Vcantm2Hwat/Vcantm2Hwat
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0009118 increased white fat cell size "increase in the size of fat cells with light coloration and few mitochondria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Vcantm2Hwat/Vcantm2Hwat
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0009285 increased gonadal fat pad weight "greater than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Vcantm2Hwat/Vcantm2Hwat
Genetic Background: involves: 129 * C57BL/6

 MP:0009288 increased epididymal fat pad weight 
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011819 increased pancreatic beta cell proliferation "increase in the ability of the cells that secrete insulin and are located towards the center of the islets of Langerhans in the pancreas to undergo expansion by cell division" [CL:0000169]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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