Manteia

ENSMUSG00000031782

Mus musculus

Features

Gene ID:	ENSMUSG00000031782

Biological name :	Coq9

Synonyms :	Coq9 / Q8K1Z0 / Ubiquinone biosynthesis protein COQ9, mitochondrial

Possible biological names infered from orthology :	coenzyme Q9 / O75208

Species:	Mus musculus

Chr. number:	8
Strand:	1
Band:	C5
Gene start:	94838321
Gene end:	94854895

Corresponding Affymetrix probe sets:	10574232 (MoGene1.0st) 1428134_at (Mouse Genome 430 2.0 Array) 1445313_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000124695 Ensembl peptide - ENSMUSP00000148339 Ensembl peptide - ENSMUSP00000034234 NCBI entrez gene - 67914 See in Manteia. MGI - MGI:1915164 RefSeq - NM_026452 RefSeq Peptide - NP_080728 swissprot - Q8K1Z0 swissprot - A0A1D5RLE9 swissprot - F6SFF5 Ensembl - ENSMUSG00000031782

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
coq9	ENSDARG00000023583	Danio rerio
COQ9	ENSGALG00000001184	Gallus gallus
COQ9	ENSG00000088682	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR012762	Ubiquinone biosynthesis protein COQ9
IPR013718	COQ9

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	IMP
biological_process	GO:0006744	ubiquinone biosynthetic process	IEA
cellular_component	GO:0005739	mitochondrion	IDA
cellular_component	GO:0005743	mitochondrial inner membrane	IBA
molecular_function	GO:0008289	lipid binding	IBA
molecular_function	GO:0042803	protein homodimerization activity	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000751	myopathy	"any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0000755	hindlimb paralysis	"loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0000921	demyelination	"loss of the myelin sheath without loss of axons or fiber tracts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0001263	weight loss	"progressive reduction of body weight below normal average for age" [J:45400]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0002183	gliosis	"increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0002654	spongiform encephalopathy	"a neurodegenerative state characterized by the appearance of large vacuolated areas in the brain cells, resembling a sponge" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0002757	reduced vertical activity	"lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0003141	cardiac fibrosis	"formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0003203	increased neuron apoptosis	"increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0003354	astrocytosis	"a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0003674	oxidative stress	"condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0005114	premature hair loss	"release of fur at an earlier than expected time" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0005319	abnormal enzyme/ coenzyme level	"altered concentration of any of these proteins, or their cofactors, that act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0006036	abnormal mitochondrial physiology		Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0008025	brain vacuoles	"the abnormal presence of cavities or fluid-filled vesicles in the soma of brain cells, often indicative of spongiosis or other pathological states" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0008143	abnormal dendrite morphology	"any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0010956	abnormal mitochondrial ATP synthesis coupled electron transport	"anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Chtf18^tm1.1KhK/Chtf18^tm1.2Khk,Alpl^tm1(cre)Nagy/Alpl⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr