ENSMUSG00000031825


Mus musculus

Features
Gene ID: ENSMUSG00000031825
  
Biological name :Crispld2
  
Synonyms : Crispld2 / Cysteine-rich secretory protein LCCL domain-containing 2 / Q8BZQ2
  
Possible biological names infered from orthology : Q9H0B8
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 119992438
Gene end: 120052793
  
Corresponding Affymetrix probe sets: 10575976 (MoGene1.0st)   1434758_at (Mouse Genome 430 2.0 Array)   1437056_x_at (Mouse Genome 430 2.0 Array)   1460458_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034282
Ensembl peptide - ENSMUSP00000104600
Ensembl peptide - ENSMUSP00000122962
NCBI entrez gene - 78892     See in Manteia.
MGI - MGI:1926142
RefSeq - XM_006531509
RefSeq - NM_001310635
RefSeq - NM_030209
RefSeq - XM_006531508
RefSeq Peptide - NP_001297564
RefSeq Peptide - NP_084485
swissprot - Q8BZQ2
Ensembl - ENSMUSG00000031825
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crispld2ENSDARG00000088595Danio rerio
 CRISPLD2ENSGALG00000032143Gallus gallus
 Q9H0B8ENSG00000103196Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CGD2 / Crispld1 / Cysteine-rich secretory protein LCCL domain-containing 1 / Q9H336*ENSMUSG0000002577659
Pi15 / peptidase inhibitor 15 / O43692*ENSMUSG0000006778028
A2A5I3 / R3hdml / R3H domain containing-like / Q9H3Y0*ENSMUSG0000007894924
Pi16 / peptidase inhibitor 16 / Q6UXB8*ENSMUSG0000002401120
Glipr1 / Q9CWG1 / Glioma pathosis-related protein 1 / P48060* / GLI pathogenesis related 1*ENSMUSG0000005688816
Q9CQ35 / Glipr1l2 / GLIPR1-like protein 2 / Q4G1C9* / GLIPR1 like 2*ENSMUSG0000002021416
Q9DAG6 / Glipr1l1 / GLIPR1-like protein 1 / Q6UWM5* / GLIPR1 like 1*ENSMUSG0000002021315
Crisp4 / cysteine-rich secretory protein 4 / CRISP1* / P54107* / cysteine rich secretory protein 1*ENSMUSG0000002577414
Crisp2 / P16563 / Cysteine-rich secretory protein 2 / P16562*ENSMUSG0000002393014
Q03401 / Crisp1 / Cysteine-rich secretory protein 1 / CRISP3* / P54108* / cysteine rich secretory protein 3*ENSMUSG0000002543114
Glipr1l3 / Q6UWM5* / GLIPR1L1* / GLIPR1 like 1*ENSMUSG0000011261114
Crisp3 / Q03402 / Cysteine-rich secretory protein 3 / P54108*ENSMUSG0000002543312


Protein motifs (from Interpro)
Interpro ID Name
 IPR001283  Cysteine-rich secretory protein, allergen V5/Tpx-1-related
 IPR004043  LCCL domain
 IPR014044  CAP domain
 IPR018244  Allergen V5/Tpx-1-related, conserved site
 IPR035940  CAP superfamily
 IPR036609  LCCL domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030198 extracellular matrix organization IDA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0060325 face morphogenesis ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0030133 transport vesicle ISO
 molecular_functionGO:0005539 glycosaminoglycan binding IDA
 molecular_functionGO:0008201 heparin binding IDA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000685 abnormal immune system morphology "morphological anomalies in the organs or cells associated with the development and formation of lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bhlha15tm3(cre/ERT2)Skz/Bhlha15tm3(cre/ERT2)Skz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cptm1b(KOMP)Wtsi/Cptm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Cptm1b(KOMP)Wtsi/J

 MP:0001790 abnormal immune system physiology "deviation from the normal function of the immune system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bhlha15tm3(cre/ERT2)Skz/Bhlha15tm3(cre/ERT2)Skz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Bhlha15tm3(cre/ERT2)Skz/Bhlha15tm3(cre/ERT2)Skz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Bhlha15tm3(cre/ERT2)Skz/Bhlha15tm3(cre/ERT2)Skz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Cptm1b(KOMP)Wtsi/Cptm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Cptm1b(KOMP)Wtsi/J

 MP:0013294 prenatal lethality prior to heart atrial septation "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]
Show

Allelic Composition: Cptm1b(KOMP)Wtsi/Cptm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Cptm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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