ENSMUSG00000032036


Mus musculus

Features
Gene ID: ENSMUSG00000032036
  
Biological name :Kirrel3
  
Synonyms : Kin of IRRE-like protein 3 Processed kin of IRRE-like protein 3 / Kirrel3 / Q8BR86
  
Possible biological names infered from orthology : kirre like nephrin family adhesion molecule 3 / Q8IZU9
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A4
Gene start: 34485894
Gene end: 35036716
  
Corresponding Affymetrix probe sets: 10584165 (MoGene1.0st)   1431402_at (Mouse Genome 430 2.0 Array)   1441357_at (Mouse Genome 430 2.0 Array)   1452728_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139714
Ensembl peptide - ENSMUSP00000139418
Ensembl peptide - ENSMUSP00000139951
Ensembl peptide - ENSMUSP00000140219
Ensembl peptide - ENSMUSP00000140086
Ensembl peptide - ENSMUSP00000048863
Ensembl peptide - ENSMUSP00000110801
Ensembl peptide - ENSMUSP00000139393
NCBI entrez gene - 67703     See in Manteia.
MGI - MGI:1914953
RefSeq - XM_017313539
RefSeq - NM_001190912
RefSeq - NM_001190913
RefSeq - NM_001190914
RefSeq - NM_026324
RefSeq - XM_006510557
RefSeq - XM_006510558
RefSeq - XM_006510559
RefSeq - XM_006510560
RefSeq - XM_006510561
RefSeq - XM_006510563
RefSeq - XM_017313538
RefSeq - NM_001190911
RefSeq Peptide - NP_001177841
RefSeq Peptide - NP_001177842
RefSeq Peptide - NP_001177843
RefSeq Peptide - NP_080600
RefSeq Peptide - NP_001177840
swissprot - A0A087WNL2
swissprot - A0A0R4J2C0
swissprot - A0A087WPC0
swissprot - G5E8B6
swissprot - A0A087WNM9
swissprot - Q8BR86
Ensembl - ENSMUSG00000032036
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01073963.1ENSDARG00000115903Danio rerio
 CABZ01112461.1ENSDARG00000113833Danio rerio
 kirrel3aENSDARG00000075806Danio rerio
 KIRREL3ENSGALG00000029197Gallus gallus
 Q8IZU9ENSG00000149571Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80W68 / Kirrel / Kin of IRRE-like protein 1 / Q96J84* / KIRREL1* / kirre like nephrin family adhesion molecule 1*ENSMUSG0000004173443
Q7TSU7 / Kirrel2 / Kin of IRRE-like protein 2 / Q6UWL6* / kirre like nephrin family adhesion molecule 2*ENSMUSG0000003691534
Nphs1 / Q9QZS7 / Nephrin / O60500* / NPHS1, nephrin*ENSMUSG0000000664921


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0002121 inter-male aggressive behavior IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IDA
 biological_processGO:0007416 synapse assembly IDA
 biological_processGO:0021740 principal sensory nucleus of trigeminal nerve development IMP
 biological_processGO:0021766 hippocampus development IMP
 biological_processGO:0030097 hemopoiesis IDA
 biological_processGO:0048812 neuron projection morphogenesis IMP
 biological_processGO:0072102 glomerulus morphogenesis IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043198 dendritic shaft IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030165 PDZ domain binding NAS


Pathways (from Reactome)
Pathway description
Nephrin family interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002566 abnormal sexual interaction "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lmnb1tm1.2Sgy/Lmnb1tm1.2Sgy
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0003862 decreased aggression towards males "when compared to controls, subjects exhibit less than normal level of domineering, assaultive posture and/or hostile physical action towards male mice " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Lmnb1tm1.2Sgy/Lmnb1tm1.2Sgy
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0009948 abnormal olfactory bulb glomerular layer morphology 
Show

Allelic Composition: Lmnb1tm1.2Sgy/Lmnb1tm1.2Sgy
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0011679 abnormal vomeronasal sensory neuron morphology "any structural anomaly of chemosensitive cells that innervate the vomernasal organ epithelium and are responsible for receiving and transmitting pheromone signals" [MGI:csmith]
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Allelic Composition: Lmnb1tm1.2Sgy/Lmnb1tm1.2Sgy
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Kirrel3tm1.1Jfcl/Kirrel3tm1.1Jfcl,Tg(Vmn2r43-lacZ*)#Ddg/0
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000006649 Nphs1 / Q9QZS7 / Nephrin / O60500* / NPHS1, nephrin*  / reaction / complex






 

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