ENSMUSG00000032078


Mus musculus

Features
Gene ID: ENSMUSG00000032078
  
Biological name :Zpr1
  
Synonyms : Q62384 / Zpr1 / ZPR1 zinc finger
  
Possible biological names infered from orthology : O75312
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A5.2
Gene start: 46273064
Gene end: 46282643
  
Corresponding Affymetrix probe sets: 10585022 (MoGene1.0st)   1419281_a_at (Mouse Genome 430 2.0 Array)   1428294_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123437
Ensembl peptide - ENSMUSP00000110199
Ensembl peptide - ENSMUSP00000117725
NCBI entrez gene - 22687     See in Manteia.
MGI - MGI:1330262
RefSeq - NM_011752
RefSeq Peptide - NP_035882
swissprot - Q62384
swissprot - F6WPJ5
swissprot - F8WHU9
Ensembl - ENSMUSG00000032078
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zpr1ENSDARG00000043542Danio rerio
 ZPR1ENSGALG00000007101Gallus gallus
 ZPR1ENSG00000109917Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004457  Zinc finger, ZPR1-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IMP
 biological_processGO:0001833 inner cell mass cell proliferation IMP
 biological_processGO:0001834 trophectodermal cell proliferation IMP
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0021510 spinal cord development IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030576 Cajal body organization IEA
 biological_processGO:0031641 regulation of myelination IMP
 biological_processGO:0033120 positive regulation of RNA splicing IEA
 biological_processGO:0042023 DNA endoreduplication IMP
 biological_processGO:0042307 positive regulation of protein import into nucleus IEA
 biological_processGO:0045927 positive regulation of growth IMP
 biological_processGO:0061564 axon development IMP
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle IEA
 biological_processGO:1902742 apoptotic process involved in development IMP
 biological_processGO:1990261 pre-mRNA catabolic process IEA
 biological_processGO:2000672 negative regulation of motor neuron apoptotic process IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0015030 Cajal body ISS
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0032797 SMN complex IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043204 perikaryon IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0097504 Gemini of coiled bodies ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IPI
 molecular_functionGO:0031369 translation initiation factor binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002718 abnormal inner cell mass "malformed or absent cells of the blastocyst that develop into the body of the embryo" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0005028 abnormal trophectoderm "malformed outermost layer of cells in the blastodermic vesicle, which will contact the endometrium and take part in establishing the embryo s means of nutrition" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0005033 abnormal trophoblast cells "anomaly of the cells covering the blastocyst that erode the uterine mucosa and contribute to the formation of the placenta " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0008888 abnormal Cajal body morphology "alteration in structure, number or location of subnuclear structures involved in snRNP biogenesis and in the trafficking of snoRNPs and snRNPs" [https://npd.hgu.mrc.ac.uk/compartments.html, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0010380 inner cell mass apoptosis "the cells of the blastocyst that develop into the body of the embryo are undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0012113 decreased inner cell mass proliferation 
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr