ENSMUSG00000032121


Mus musculus

Features
Gene ID: ENSMUSG00000032121
  
Biological name :Tmem218
  
Synonyms : Q9CQ44 / Tmem218 / Transmembrane protein 218
  
Possible biological names infered from orthology : A2RU14
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A4
Gene start: 37208223
Gene end: 37224700
  
Corresponding Affymetrix probe sets: 10584271 (MoGene1.0st)   1417174_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034632
NCBI entrez gene - 66279     See in Manteia.
MGI - MGI:1913529
RefSeq - XM_006510546
RefSeq - NM_001310096
RefSeq - NM_025464
RefSeq Peptide - NP_079740
RefSeq Peptide - NP_001297025
swissprot - Q9CQ44
Ensembl - ENSMUSG00000032121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7SZ56ENSDARG00000027129Danio rerio
 A2RU14ENSG00000150433Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026771  Transmembrane protein 218


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000194 hypercalcemia "abnormally high concentration of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0000522 cysts in kidney cortex "abnormal membranous sacs appearing in the renal lobules, tubules and glomeruli" [J:50844]
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Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0002090 abnormal vision "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0002703 abnormal renal tubules "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0003019 increased circulating chloride level "elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0003215 renal interstitial fibrosis "formation of fibrous tissue within the interstices of the kidney as a result of repair or a reactive process" [RGD:Rat Genome Database submission]
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Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0003675 kidney cysts "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0005553 increased circulating creatinine level "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0006144 increased systolic blood pressure "abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0011346 renal tubule atrophy "acquired diminution of the size of the loops of Henle, the proximal convoluted tubule or the distal convoluted tubule associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

 MP:0012029 abnormal electroretinogram waveform feature "any anomaly in the pattern of the graphic record of the integrated ensemble response from many vision related neuronal and glial populations as a consequence of the serial processing within the retina, represented as changes in voltage over time after visual photonic stimulation" [MGI:csmith]
Show

Allelic Composition: Dysfim/Dysfim,Large1myd/Large1myd
Genetic Background: involves: C57BL/6 * SJL/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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