ENSMUSG00000032123


Mus musculus

Features
Gene ID: ENSMUSG00000032123
  
Biological name :Dpagt1
  
Synonyms : Dpagt1 / P42867 / UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
  
Possible biological names infered from orthology : dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 / Q9H3H5
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A5.2
Gene start: 44326019
Gene end: 44333900
  
Corresponding Affymetrix probe sets: 10584700 (MoGene1.0st)   1448549_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000150465
Ensembl peptide - ENSMUSP00000056282
Ensembl peptide - ENSMUSP00000150178
NCBI entrez gene - 13478     See in Manteia.
MGI - MGI:1196396
RefSeq - XM_006509995
RefSeq - NM_007875
RefSeq - XM_006509991
RefSeq - XM_006509992
RefSeq - XM_006509994
RefSeq Peptide - NP_031901
swissprot - A0A1L1STS5
swissprot - A0A1L1ST50
swissprot - P42867
Ensembl - ENSMUSG00000032123
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpagt1ENSDARG00000061061Danio rerio
 DPAGT1ENSGALG00000032420Gallus gallus
 DPAGT1ENSG00000172269Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000715  Glycosyl transferase, family 4
 IPR033895  UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006047 UDP-N-acetylglucosamine metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006487 protein N-linked glycosylation ISO
 biological_processGO:0006488 dolichol-linked oligosaccharide biosynthetic process TAS
 biological_processGO:0006489 dolichyl diphosphate biosynthetic process IBA
 biological_processGO:0019348 dolichol metabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003975 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity ISO
 molecular_functionGO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity ISS
 molecular_functionGO:0008963 phospho-N-acetylmuramoyl-pentapeptide-transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Car14tm1Sly/Car14tm1Sly,Car4tm1Sly/Car4tm1Sly
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0003694 failure to hatch from the zona pellucida "the embryo fails to break out of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, may be seen in vivo or in cultured embryos" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Car14tm1Sly/Car14tm1Sly,Car4tm1Sly/Car4tm1Sly
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
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Allelic Composition: Car14tm1Sly/Car14tm1Sly,Car4tm1Sly/Car4tm1Sly
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Slc12a6Gt(OST458419)Lex/Slc12a6Gt(OST458419)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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