ENSMUSG00000032181


Mus musculus

Features
Gene ID: ENSMUSG00000032181
  
Biological name :Scg3
  
Synonyms : P47867 / Scg3 / Secretogranin-3
  
Possible biological names infered from orthology : Q8WXD2 / secretogranin III
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: D
Gene start: 75643189
Gene end: 75684056
  
Corresponding Affymetrix probe sets: 10595033 (MoGene1.0st)   1448628_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151074
Ensembl peptide - ENSMUSP00000152480
Ensembl peptide - ENSMUSP00000034699
Ensembl peptide - ENSMUSP00000149561
NCBI entrez gene - 20255     See in Manteia.
MGI - MGI:103032
RefSeq - XM_006510881
RefSeq - XM_017313220
RefSeq - NM_001164790
RefSeq - NM_009130
RefSeq Peptide - NP_001158262
RefSeq Peptide - NP_033156
swissprot - P47867
swissprot - A0A1Y7VLI5
swissprot - A0A1L1SV66
Ensembl - ENSMUSG00000032181
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scg3ENSDARG00000086288Danio rerio
 SCG3ENSGALG00000043583Gallus gallus
 SCG3ENSG00000104112Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026197  Secretogranin III


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tnftm2Gkl/Tnf+
Genetic Background: B6.129S-Tnftm2Gkl/Jarn

 MP:0002693 abnormal pancreas physiology "abberrant function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tmem59tm1.1Tqw/Tmem59tm1.1Tqw,Tg(Thy1-EGFP)MJrs/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Tmem59tm1.1Tqw/Tmem59tm1.1Tqw,Tg(Thy1-EGFP)MJrs/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tmem59tm1.1Tqw/Tmem59tm1.1Tqw,Tg(Thy1-EGFP)MJrs/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA

 MP:0005646 abnormal pituitary gland physiology "anmalous function of this unpaired compound gland suspended from the base of the hypothalamus by a short extension of the infundibulum, the infundibular or pituitary stalk" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tmem59tm1.1Tqw/Tmem59tm1.1Tqw,Tg(Thy1-EGFP)MJrs/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA

 MP:0005658 susceptibility to diet-induced obesity "more likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator]
Show

Allelic Composition: Tmem59tm1.1Tqw/Tmem59tm1.1Tqw,Tg(Thy1-EGFP)MJrs/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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