ENSMUSG00000032252


Mus musculus

Features
Gene ID: ENSMUSG00000032252
  
Biological name :Glce
  
Synonyms : D-glucuronyl C5-epimerase / Glce / Q9EPS3
  
Possible biological names infered from orthology : glucuronic acid epimerase / O94923
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: B
Gene start: 62057248
Gene end: 62122655
  
Corresponding Affymetrix probe sets: 10594289 (MoGene1.0st)   1425876_a_at (Mouse Genome 430 2.0 Array)   1428374_at (Mouse Genome 430 2.0 Array)   1440386_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140671
Ensembl peptide - ENSMUSP00000034785
Ensembl peptide - ENSMUSP00000139949
NCBI entrez gene - 93683     See in Manteia.
MGI - MGI:2136405
RefSeq - NM_033320
RefSeq - XM_006511571
RefSeq - XM_006511572
RefSeq Peptide - NP_201577
swissprot - A0A087WRK5
swissprot - Q9EPS3
Ensembl - ENSMUSG00000032252
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glceaENSDARG00000005095Danio rerio
 glcebENSDARG00000068981Danio rerio
 GLCEENSGALG00000028191Gallus gallus
 GLCEENSG00000138604Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010598  D-glucuronyl C5-epimerase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006024 glycosaminoglycan biosynthetic process IEA
 biological_processGO:0015012 heparan sulfate proteoglycan biosynthetic process ISO
 biological_processGO:0030210 heparin biosynthetic process IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives IMP
 molecular_functionGO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity ISO
 molecular_functionGO:0050379 UDP-glucuronate 5"-epimerase activity TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000157 abnormal sternum morphology "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000520 absent kidney "missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001175 abnormal lung morphology "malformed organ of respiration" [J:35802]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0003051 curly tail "a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004624 abnormal thoracic cage "any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005306 abnormal phalanx morphology "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0009729 absent tarsus bones "absence of the eight bones of the instep of the paw/foot: tibiale, talus, calcaneus, navicular, 3 cuneiform, and cuboid bones" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0010714 coloboma of the iris "congenital defect of the iris in which some part of the structure is absent" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0010903 abnormal pulmonary alveolus wall morphology 
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Prdx1tm1Rave/Prdx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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