ENSMUSG00000032258


Mus musculus

Features
Gene ID: ENSMUSG00000032258
  
Biological name :Lca5
  
Synonyms : Lca5 / LCA5, lebercilin
  
Possible biological names infered from orthology : Q86VQ0
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E2
Gene start: 83390293
Gene end: 83441127
  
Corresponding Affymetrix probe sets: 10595382 (MoGene1.0st)   1428799_at (Mouse Genome 430 2.0 Array)   1430340_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139529
Ensembl peptide - ENSMUSP00000140753
Ensembl peptide - ENSMUSP00000140334
Ensembl peptide - ENSMUSP00000034791
Ensembl peptide - ENSMUSP00000034793
NCBI entrez gene - 75782     See in Manteia.
MGI - MGI:1923032
RefSeq - XM_006511534
RefSeq - XM_006511535
RefSeq - XM_011242832
RefSeq - XM_006511538
RefSeq - XM_006511537
RefSeq - NM_027448
RefSeq - NM_029434
RefSeq - XM_011242833
RefSeq - XM_006511536
RefSeq Peptide - NP_083710
RefSeq Peptide - NP_081724
swissprot - A0A087WRS6
swissprot - A0A087WNX0
swissprot - G5E887
swissprot - G5E886
swissprot - A0A087WQT5
Ensembl - ENSMUSG00000032258
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lca5ENSDARG00000076153Danio rerio
 LCA5ENSGALG00000015878Gallus gallus
 LCA5ENSG00000135338Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lca5l / LCA5L, lebercilin like / O95447*ENSMUSG0000004527521


Protein motifs (from Interpro)
Interpro ID Name
 IPR026188  Lebercilin-like
 IPR026684  Lebercilin
 IPR028933  Lebercilin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005929 cilium IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003728 abnormal photoreceptor layer "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0003729 abnormal photoreceptor outer segments "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0005103 abnormal retinal pigmentation "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0008582 short photoreceptor inner segment "decreased length of the photoreceptor region which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc) and where opsin molecules are assembled and passed to be part of the outer segment region" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0008586 disorganized photoreceptor outer segment "derangement of the pattern of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

 MP:0008587 short photoreceptor outer segment "decreased length of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mir140tm1.1Tkob/Mir140tm1.1Tkob,Pdgfratm8Sor/Pdgfratm8Sor,Tg(Col2a1-cre)1Rsjo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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