ENSMUSG00000032436


Mus musculus

Features
Gene ID: ENSMUSG00000032436
  
Biological name :Cmtm7
  
Synonyms : CKLF-like MARVEL transmembrane domain-containing protein 7 / Cmtm7 / Q9ESD6
  
Possible biological names infered from orthology : CKLF like MARVEL transmembrane domain containing 7 / Q96FZ5
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F3
Gene start: 114756836
Gene end: 114781856
  
Corresponding Affymetrix probe sets: 10597461 (MoGene1.0st)   1451702_at (Mouse Genome 430 2.0 Array)   1460253_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000149591
Ensembl peptide - ENSMUSP00000035009
Ensembl peptide - ENSMUSP00000081927
NCBI entrez gene - 102545     See in Manteia.
MGI - MGI:2447166
RefSeq - NM_001252479
RefSeq - NM_133978
RefSeq Peptide - NP_001239408
RefSeq Peptide - NP_598739
swissprot - A0A1L1SRR1
swissprot - Q9ESD6
Ensembl - ENSMUSG00000032436
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cmtm7ENSDARG00000010032Danio rerio
 CMTM7ENSGALG00000011488Gallus gallus
 CMTM7ENSG00000153551Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008253  Marvel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002337 B-1a B cell differentiation IMP
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005125 cytokine activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001806 decreased IgM "less than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cmtm7tm2a(EUCOMM)Hmgu/Cmtm7+,Rag1tm1Fwa/Rag1tm1Fwa
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0002459 abnormal B cell physiology "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: CrygbS11R/CrygbS11R,Gja8tm1(Gja3)Tww/Gja8tm1(Gja3)Tww
Genetic Background: involves: A/J * C57BL/6J

 MP:0005093 impaired B cell proliferation "absent or reduced ability of B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cmtm7tm2a(EUCOMM)Hmgu/Cmtm7+,Rag1tm1Fwa/Rag1tm1Fwa
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0008098 decreased plasma cell number "reduced number of terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin" [CL:0000786, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cmtm7tm2a(EUCOMM)Hmgu/Cmtm7+,Rag1tm1Fwa/Rag1tm1Fwa
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0008164 abnormal B-1a B cell morphology "any structural anomaly of the B-1 B cell subset bearing the CD5 surface marker" [CL:0000820, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:11861604]
Show

Allelic Composition: Cmtm7tm2a(EUCOMM)Hmgu/Cmtm7+,Rag1tm1Fwa/Rag1tm1Fwa
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0008168 decreased B-1a cell number "reduced number of the B-1 B cell subset bearing the CD5 surface marker" [CL:0000820, PMID:11861604]
Show

Allelic Composition: Cmtm7tm2a(EUCOMM)Hmgu/Cmtm7+,Rag1tm1Fwa/Rag1tm1Fwa
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0008497 decreased IgG2b level "less than normal immunoglobulin class G2b level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cmtm7tm2a(EUCOMM)Hmgu/Cmtm7+,Rag1tm1Fwa/Rag1tm1Fwa
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: CrygbS11R/CrygbS11R,Gja8tm1(Gja3)Tww/Gja8tm1(Gja3)Tww
Genetic Background: involves: A/J * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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