ENSMUSG00000032463


Mus musculus

Features
Gene ID: ENSMUSG00000032463
  
Biological name :Faim
  
Synonyms : Faim / Fas apoptotic inhibitory molecule 1 / Q9WUD8
  
Possible biological names infered from orthology : Fas apoptotic inhibitory molecule / Q9NVQ4
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E3.3
Gene start: 98986373
Gene end: 99002021
  
Corresponding Affymetrix probe sets: 10588083 (MoGene1.0st)   1418029_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108532
Ensembl peptide - ENSMUSP00000140627
Ensembl peptide - ENSMUSP00000035038
NCBI entrez gene - 23873     See in Manteia.
MGI - MGI:1344387
RefSeq - NM_011810
RefSeq - NM_001122851
RefSeq Peptide - NP_001116323
RefSeq Peptide - NP_035940
swissprot - Q9WUD8
swissprot - D3Z3C1
swissprot - A0A087WRH2
Ensembl - ENSMUSG00000032463
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 faimaENSDARG00000005828Danio rerio
 faimbENSDARG00000020814Danio rerio
 FAIMENSGALG00000012082Gallus gallus
 FAIMENSG00000158234Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Faiml / FAIM* / Q9NVQ4* / Fas apoptotic inhibitory molecule*ENSMUSG0000009631669


Protein motifs (from Interpro)
Interpro ID Name
 IPR010695  Fas apoptotic inhibitory molecule 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IDA
 cellular_componentGO:0005737 cytoplasm IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001860 liver inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0002941 increased circulating alanine transaminase level "increased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003326 liver failure "cessation of function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003887 increased hepatocyte apoptosis "increase in the number of hepatocytes undergoing programmed cell death" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003888 liver hemorrhage "bleeding within the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0008782 increased B cell apoptosis "increase in the timing or the number of B cells undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009541 increased thymocyte apoptosis "increase in the number of immature T cells located in the thymus that are undergoing programmed cell death" [CL:0000893, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009766 increased sensitivity to xenobiotic induced morbidity/mortality "decrease in the amount of a foreign compound required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2tm1Ifc
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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