ENSMUSG00000032536


Mus musculus

Features
Gene ID: ENSMUSG00000032536
  
Biological name :Trak1
  
Synonyms : Q6PD31 / trafficking protein, kinesin binding 1 / Trak1
  
Possible biological names infered from orthology : Q9UPV9 / trafficking kinesin protein 1
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F4
Gene start: 121297502
Gene end: 121474918
  
Corresponding Affymetrix probe sets: 10590343 (MoGene1.0st)   1428327_at (Mouse Genome 430 2.0 Array)   1452742_at (Mouse Genome 430 2.0 Array)   1456755_at (Mouse Genome 430 2.0 Array)   1459666_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000147604
Ensembl peptide - ENSMUSP00000147571
Ensembl peptide - ENSMUSP00000147624
Ensembl peptide - ENSMUSP00000148092
Ensembl peptide - ENSMUSP00000148026
Ensembl peptide - ENSMUSP00000148017
Ensembl peptide - ENSMUSP00000147885
Ensembl peptide - ENSMUSP00000147805
Ensembl peptide - ENSMUSP00000147646
Ensembl peptide - ENSMUSP00000044482
NCBI entrez gene - 67095     See in Manteia.
MGI - MGI:1914345
RefSeq - XM_017313525
RefSeq - XM_006512224
RefSeq - XM_006512225
RefSeq - XM_006512226
RefSeq - XM_006512227
RefSeq - XM_006512229
RefSeq - XM_006512233
RefSeq - XM_006512234
RefSeq - XM_011242990
RefSeq - XM_011242991
RefSeq - XM_011242992
RefSeq - XM_011242994
RefSeq - XM_017313521
RefSeq - XM_017313522
RefSeq - XM_017313523
RefSeq - XM_017313524
RefSeq - NM_001357968
RefSeq - NM_001357969
RefSeq - NM_001357972
RefSeq - NM_001357973
RefSeq - NM_175114
RefSeq Peptide - NP_001344901
RefSeq Peptide - NP_001344902
RefSeq Peptide - NP_780323
RefSeq Peptide - NP_001344897
RefSeq Peptide - NP_001344898
swissprot - A0A1B0GRQ7
swissprot - A0A1B0GRP1
swissprot - A0A1B0GRL4
swissprot - A0A1B0GSQ2
swissprot - Q6PD31
swissprot - Q80VE1
swissprot - A0A1B0GSP3
swissprot - A0A1B0GSC9
swissprot - A0A1B0GS60
swissprot - A0A1B0GRS7
Ensembl - ENSMUSG00000032536
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trak1aENSDARG00000041304Danio rerio
 TRAK1ENSGALG00000038733Gallus gallus
 TRAK1ENSG00000182606Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trak2 / trafficking protein, kinesin binding 2 / O60296* / trafficking kinesin protein 2*ENSMUSG0000002602846
Hap1 / O35668 / Huntingtin-associated protein 1 / P54257*ENSMUSG0000000693015


Protein motifs (from Interpro)
Interpro ID Name
 IPR006933  HAP1, N-terminal
 IPR022154  Trafficking kinesin-binding protein domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008333 endosome to lysosome transport IEA
 biological_processGO:0019896 axonal transport of mitochondrion IEA
 biological_processGO:0048813 dendrite morphogenesis IEA
 biological_processGO:0050772 positive regulation of axonogenesis IEA
 biological_processGO:0098957 anterograde axonal transport of mitochondrion IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0044295 axonal growth cone IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0030911 TPR domain binding IEA
 molecular_functionGO:0050811 GABA receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Destm1Cba/Destm1Cba
Genetic Background: involves: 129S2/SvPas

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
Show

Allelic Composition: Spi1tm1Kast/Spi1+
Genetic Background: B6.129S2-Spi1tm1Kast

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Spi1tm1Kast/Spi1+
Genetic Background: B6.129S2-Spi1tm1Kast

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Destm1Cba/Destm1Cba
Genetic Background: involves: 129S2/SvPas

 MP:0001504 abnormal posture "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
Show

Allelic Composition: Spi1tm1Kast/Spi1+
Genetic Background: B6.129S2-Spi1tm1Kast

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
Show

Allelic Composition: Destm1Cba/Destm1Cba
Genetic Background: involves: 129S2/SvPas

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Destm1Cba/Destm1Cba
Genetic Background: involves: 129S2/SvPas

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Destm1Cba/Destm1Cba
Genetic Background: involves: 129S2/SvPas

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Destm1Cba/Destm1Cba
Genetic Background: involves: 129S2/SvPas

 MP:0005424 jerky movement "continuous, abrupt, faltering motions of the whole body or a portion of the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Destm1Cba/Destm1Cba
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr