ENSMUSG00000032557


Mus musculus

Features
Gene ID: ENSMUSG00000032557
  
Biological name :Uba5
  
Synonyms : Q8VE47 / Uba5 / ubiquitin-like modifier activating enzyme 5
  
Possible biological names infered from orthology : Q9GZZ9
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F1
Gene start: 104046599
Gene end: 104063134
  
Corresponding Affymetrix probe sets: 10596207 (MoGene1.0st)   1435247_at (Mouse Genome 430 2.0 Array)   1451973_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118535
Ensembl peptide - ENSMUSP00000149909
Ensembl peptide - ENSMUSP00000118734
Ensembl peptide - ENSMUSP00000035166
NCBI entrez gene - 66663     See in Manteia.
MGI - MGI:1913913
RefSeq - XM_006511791
RefSeq - NM_025692
RefSeq Peptide - NP_079968
swissprot - A0A1L1SSH6
swissprot - D6RH76
swissprot - Q8VE47
swissprot - F6VRI6
Ensembl - ENSMUSG00000032557
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uba5ENSDARG00000063588Danio rerio
 UBA5ENSGALG00000032382Gallus gallus
 UBA5ENSG00000081307Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000594  THIF-type NAD/FAD binding fold
 IPR029752  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
 IPR035985  Ubiquitin-activating enzyme


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0033146 regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:0071569 protein ufmylation IEA
 biological_processGO:1990592 protein K69-linked ufmylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008641 ubiquitin-like modifier activating enzyme activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0071566 UFM1 activating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Chd6tm1.2Fier/Chd6tm1.2Fier
Genetic Background: 129S1/SvImJ-Chd6tm1.2Fier

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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