ENSMUSG00000032724


Mus musculus

Features
Gene ID: ENSMUSG00000032724
  
Biological name :Abtb2
  
Synonyms : Abtb2 / ankyrin repeat and BTB (POZ) domain containing 2 / Q7TQI7
  
Possible biological names infered from orthology : ankyrin repeat and BTB domain containing 2 / Q8N961
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E2
Gene start: 103566310
Gene end: 103718423
  
Corresponding Affymetrix probe sets: 10474181 (MoGene1.0st)   1433453_a_at (Mouse Genome 430 2.0 Array)   1433454_at (Mouse Genome 430 2.0 Array)   1444771_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000075566
NCBI entrez gene - 99382     See in Manteia.
MGI - MGI:2139365
RefSeq - NM_178890
RefSeq Peptide - NP_849221
swissprot - Q3T9J9
swissprot - Q7TQI7
Ensembl - ENSMUSG00000032724
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abtb2aENSDARG00000059751Danio rerio
 abtb2bENSDARG00000062000Danio rerio
 ENSGALG00000011609Gallus gallus
 ENSGALG00000031889Gallus gallus
 ABTB2ENSG00000166016Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Btbd11 / Q6GQW0 / Ankyrin repeat and BTB/POZ domain-containing protein BTBD11 / A6QL63* / BTB domain containing 11*ENSMUSG0000002004257


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR002110  Ankyrin repeat
 IPR009072  Histone-fold
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030162 regulation of proteolysis IBA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0097237 cellular response to toxic substance IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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