MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0001364 | decreased anxiety-related response | "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0001399 | hyperactivity | "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0001409 | increased stereotypic behavior | "more frequent incidence of repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, MGI:CLS, J:57125] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0001440 | abnormal grooming behavior | "defects in the standard of behavior of cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0002574 | increased vertical activity | "greater than average time spent jumping or rearing " [J:72576, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0008462 | abnormal medium spiny neuron morphology | "any structural anomaly of the inhibitory projection neurons located in the striatum that integrate glutamatergic signals arising from the cerebral cortex and thalamus" [PMID:15504319] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0012468 | decreased striatum area | "reduced size of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [ISBN:0838580343, MGI:csmith] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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MP:0013894 | abnormal behavioral response to amphetamine | "anomaly in the behavioral response induced by amphetamine such as induced hyperactivity or stereotypic behavior" [MGI:smb] |
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Allelic Composition: Pdia4tm1b(EUCOMM)Wtsi/Pdia4tm1b(EUCOMM)Wtsi,Tg(Tek-cre)12Flv/0 Genetic Background: involves: C3H * C57BL/6N
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