ENSMUSG00000033386


Mus musculus

Features
Gene ID: ENSMUSG00000033386
  
Biological name :Frrs1
  
Synonyms : ferric chelate reductase 1 / Frrs1
  
Possible biological names infered from orthology : Q6ZNA5
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: G1
Gene start: 116859464
Gene end: 116908177
  
Corresponding Affymetrix probe sets: 10495596 (MoGene1.0st)   1423465_at (Mouse Genome 430 2.0 Array)   1460141_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039487
Ensembl peptide - ENSMUSP00000143546
Ensembl peptide - ENSMUSP00000143255
Ensembl peptide - ENSMUSP00000142793
NCBI entrez gene - 20321     See in Manteia.
MGI - MGI:108076
RefSeq - XM_017319511
RefSeq - NM_001113478
RefSeq - NM_009146
RefSeq - XM_006501185
RefSeq Peptide - NP_001106950
RefSeq Peptide - NP_033172
swissprot - A0A0G2JGF6
swissprot - A0A0G2JEJ3
swissprot - A0A0G2JFP4
Ensembl - ENSMUSG00000033386
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 frrs1aENSDARG00000076183Danio rerio
 frrs1bENSDARG00000077605Danio rerio
 FRRS1ENSGALG00000005418Gallus gallus
 FRRS1ENSG00000156869Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B1AXV0 / Frrs1l / DOMON domain-containing protein FRRS1L / Q9P0K9* / ferric chelate reductase 1 like*ENSMUSG0000004558912


Protein motifs (from Interpro)
Interpro ID Name
 IPR002861  Reeler domain
 IPR005018  DOMON domain
 IPR006593  Cytochrome b561/ferric reductase transmembrane


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Fgfr1tm1.1(KOMP)Vlcg/Fgfr1+
Genetic Background: C57BL/6N-Fgfr1tm1.1(KOMP)Vlcg/Ucd

 MP:0005477 increased circulating thyroxine level "greater than the normal blood concentration of the major hormone dervied from the thryoid gland; it normally affects cellular metabolism" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Fgfr1tm1.1(KOMP)Vlcg/Fgfr1+
Genetic Background: C57BL/6N-Fgfr1tm1.1(KOMP)Vlcg/Ucd

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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