ENSMUSG00000033411


Mus musculus

Features
Gene ID: ENSMUSG00000033411
  
Biological name :Ctdspl2
  
Synonyms : CTD small phosphatase-like protein 2 / Ctdspl2 / Q8BG15
  
Possible biological names infered from orthology : CTD small phosphatase like 2 / Q05D32
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E5
Gene start: 121956001
Gene end: 122013642
  
Corresponding Affymetrix probe sets: 10467368 (MoGene1.0st)   10475394 (MoGene1.0st)   1435320_at (Mouse Genome 430 2.0 Array)   1436914_at (Mouse Genome 430 2.0 Array)   1440740_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047543
Ensembl peptide - ENSMUSP00000106201
Ensembl peptide - ENSMUSP00000106203
Ensembl peptide - ENSMUSP00000106207
NCBI entrez gene - 329506     See in Manteia.
MGI - MGI:1196405
RefSeq - XM_006499776
RefSeq - NM_001290991
RefSeq - NM_001290992
RefSeq - NM_212450
RefSeq Peptide - NP_001277921
RefSeq Peptide - NP_997615
RefSeq Peptide - NP_001277920
swissprot - Q8BG15
Ensembl - ENSMUSG00000033411
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A4QNX6ENSDARG00000060586Danio rerio
 Q08BB5ENSDARG00000061587Danio rerio
 CTDSPL2ENSGALG00000008199Gallus gallus
 Q05D32ENSG00000137770Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004274  FCP1 homology domain
 IPR011948  Dullard phosphatase domain, eukaryotic
 IPR023214  HAD superfamily
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IMP
 biological_processGO:0030514 negative regulation of BMP signaling pathway IMP
 biological_processGO:0046827 positive regulation of protein export from nucleus IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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