ENSMUSG00000033578


Mus musculus

Features
Gene ID: ENSMUSG00000033578
  
Biological name :Tmem35a
  
Synonyms : Q9D328 / Tmem35a / Transmembrane protein 35A
  
Possible biological names infered from orthology : Q53FP2
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: E3
Gene start: 134295225
Gene end: 134305969
  
Corresponding Affymetrix probe sets: 10601701 (MoGene1.0st)   1416710_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044926
NCBI entrez gene - 67564     See in Manteia.
MGI - MGI:1914814
RefSeq - NM_026239
RefSeq Peptide - NP_080515
swissprot - Q9D328
Ensembl - ENSMUSG00000033578
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem35ENSDARG00000052567Danio rerio
 TMEM35AENSGALG00000005041Gallus gallus
 Q53FP2ENSG00000126950Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029693  Transmembrane protein 35A
 IPR032808  DoxX family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000693 spleen hyperplasia "increased cell number in the spleen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0001473 reduced long term potentiation "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0001745 increased circulating corticosterone level "greater than the normal concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:54931]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0002806 abnormal conditioned emotional response "defects in an emotional response that has been acquired by conditioning " [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0003460 decreased fear-related response "reduced emotional response related to anticipation of specific pain or danger" [CFG:Center for Functional Genomics, Northwestern University]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0008432 abnormal long-term spatial reference memory "anomaly in long-term memory for spatial location information that is consolidated over hours and days after training or an encounter at that location" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0009078 adrenal gland hyperplasia "overdevelopment or increased size, usually due to a increased number of cells, of the endocrine glands located above the kidney and responsible for hormone and epinephrine secretion" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0009454 impaired contextual conditioning "decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

 MP:0009456 impaired cued conditioning behavior "decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light flash)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tlr3M2Btlr/Tlr3+
Genetic Background: C57BL/6J-Tlr3M2Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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