ENSMUSG00000034387


Mus musculus

Features
Gene ID: ENSMUSG00000034387
  
Biological name :Ssu2
  
Synonyms : Mus musculus ssu-2 homolog (C. elegans) (Ssu2), transcript variant 2, mRNA. / Q8C3L1 / Ssu2
  
Possible biological names infered from orthology : Q9Y2M2 / ssu-2 homolog (C. elegans) / SSUH2
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: E3
Gene start: 112359324
Gene end: 112388023
  
Corresponding Affymetrix probe sets: 10546817 (MoGene1.0st)   1440642_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052328
NCBI entrez gene - 243612     See in Manteia.
MGI - MGI:2443733
RefSeq - XM_017321587
RefSeq - NM_001356365
RefSeq - NM_175525
RefSeq - XM_006506109
RefSeq - XM_006506110
RefSeq - XM_017321586
RefSeq Peptide - NP_780734
RefSeq Peptide - NP_001343294
swissprot - Q8C3L1
Ensembl - ENSMUSG00000034387
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ssuh2.1ENSDARG00000040938Danio rerio
 SSUH2ENSG00000125046Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001305  Heat shock protein DnaJ, cysteine-rich domain
 IPR033271  Protein SSUH2 homologue
 IPR036410  Heat shock protein DnaJ, cysteine-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042476 odontogenesis IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002100 abnormal tooth morphology "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

Allelic Composition: Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0002818 abnormal dentin morphology "defects in the hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

Allelic Composition: Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0002819 abnormal pulp cavity morphology "defects in the central hollow space of a tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

Allelic Composition: Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0013250 abnormal dental pulp morphology "any structural anomaly of the soft tissue within the pulp cavity located in the center of a tooth, comprised of living connective tissue containing blood vessels, nerves and lymphatics, and a layer of odontoblasts at the periphery, which participate in dentin repair" [ISBN:068340007X, MGI:csmith]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

Allelic Composition: Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0030451 abnormal dentin mineralization "anomaly in the process by which calcium salts are deposited into dentin" [GO:0097188]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

Allelic Composition: Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0030455 increased odontoblast number "greater than normal number of the skeletogenic cells on the outer surface of the dental pulp that secrete dentin matrix, are derived from the odontogenic papilla, and develop from preodontoblast cells" [MGI:anna]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

Allelic Composition: Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0030459 abnormal tooth attrition "change in the physiologic wearing away of tooth structure as a result of abnormal tooth-to-tooth contact, as in mastication, occurring only on the occlusal, incisal, and proximal surfaces" [PMID:22240686, RDO:0007259]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

Allelic Composition: Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0030543 abnormal predentin morphology "any structural anomaly of the initial type I collagen-rich unmineralized extracellular matrix synthesized and secreted by odontoblasts and located at the dentin-pulp interface; predentin is converted to dentin when hydroxyapatite crystals are deposited on the predentin" [https://books.google.com/books?isbn=0470958332]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

Allelic Composition: Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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