ENSMUSG00000034854


Mus musculus

Features
Gene ID: ENSMUSG00000034854
  
Biological name :Mfsd12
  
Synonyms : Major facilitator superfamily domain-containing protein 12 / Mfsd12 / Q3U481
  
Possible biological names infered from orthology : major facilitator superfamily domain containing 12 / Q6NUT3
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 81357491
Gene end: 81366225
  
Corresponding Affymetrix probe sets: 10365104 (MoGene1.0st)   1434263_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120259
Ensembl peptide - ENSMUSP00000036116
NCBI entrez gene - 73822     See in Manteia.
MGI - MGI:3604804
RefSeq - NM_028657
RefSeq - XM_006514219
RefSeq Peptide - NP_082933
swissprot - D6RJ45
swissprot - Q3U481
Ensembl - ENSMUSG00000034854
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mfsd12aENSDARG00000061908Danio rerio
 MFSD12ENSGALG00000000795Gallus gallus
 MFSD12ENSG00000161091Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000371 diluted coat color "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0000454 abnormal jaw morphology "malformation of the bony framework of the mouth where the teeth are held" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0000585 kinked tail "a sharp bend or zig-zag in the tail" [J:61295]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0001259 abnormal body weight "anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0001928 abnormal ovulation "aberration in the release of an ovum from a rupturing Graafin follicle, normally regulated by a surge in lutenizing hormone" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0002089 abnormal postnatal growth/weight/body size "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0002111 abnormal tail morphology "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0002116 abnormal craniofacial bone morphology "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0003355 reduced ovulation "reduction in the frequency in which an ovum is released from a rupturing ovarian follicle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0004994 abnormal brain wave pattern "any anomaly in the standard pattern of rhythmic and rapid fluctuation of electrical potential between parts of the brain, often visualized on an electroencephalogram (EEG); the pattern is often measured to diagnose neurological conditions such as seizure disorders (epilepsy)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ap3d1mh Mfsd12+/Ap3d1+ Mfsd12gr
Genetic Background: STOCK Mfsd12gr +/+ Ap3d1mh/J

 MP:0005171 lack of coat pigmentation "fur is devoid of coloration and appears white " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ

 MP:0012017 grizzled coat color "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreased compared to wild-type agouti producing hair that is partly gray or streaked with gray" [MGI:llw2]
Show

Allelic Composition: Cfap69tm1c(KOMP)Wtsi/Cfap69tm1c(KOMP)Wtsi,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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