ENSMUSG00000034936


Mus musculus

Features
Gene ID: ENSMUSG00000034936
  
Biological name :Arl4d
  
Synonyms : ADP-ribosylation factor-like protein 4D / Arl4d / Q99PE9
  
Possible biological names infered from orthology : ADP ribosylation factor like GTPase 4D / P49703
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 101665541
Gene end: 101667832
  
Corresponding Affymetrix probe sets: 10381474 (MoGene1.0st)   1418250_at (Mouse Genome 430 2.0 Array)   1450358_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035918
NCBI entrez gene - 80981     See in Manteia.
MGI - MGI:1933155
RefSeq - NM_025404
RefSeq Peptide - NP_079680
swissprot - Q99PE9
Ensembl - ENSMUSG00000034936
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arl4dENSDARG00000045074Danio rerio
 ARL4DENSG00000175906Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arl4a / P61213 / ADP-ribosylation factor-like protein 4A / P40617* / ADP ribosylation factor like GTPase 4A*ENSMUSG0000004744660
Arl4c / P61208 / ADP-ribosylation factor-like protein 4C / P56559* / ADP ribosylation factor like GTPase 4C*ENSMUSG0000004986657


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0004648 decreased thoracic vertebrae number "reduced number of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0010101 increased sacral vertebrae number "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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