ENSMUSG00000035139


Mus musculus

Features
Gene ID: ENSMUSG00000035139
  
Biological name :Secisbp2
  
Synonyms : SECIS binding protein 2 / Secisbp2
  
Possible biological names infered from orthology : Q96T21
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 51651697
Gene end: 51684044
  
Corresponding Affymetrix probe sets: 10405191 (MoGene1.0st)   1428496_at (Mouse Genome 430 2.0 Array)   1428497_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045740
Ensembl peptide - ENSMUSP00000105671
NCBI entrez gene - 75420     See in Manteia.
MGI - MGI:1922670
RefSeq - XM_006516966
RefSeq - NM_001308448
RefSeq - NM_029279
RefSeq - XM_006516964
RefSeq - XM_006516965
RefSeq Peptide - NP_001295377
RefSeq Peptide - NP_083555
swissprot - Q8BYU9
swissprot - Q3U1C4
Ensembl - ENSMUSG00000035139
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 secisbp2ENSDARG00000073892Danio rerio
 SECISBP2ENSGALG00000010694Gallus gallus
 Q96T21ENSG00000187742Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Secisbp2l / SECIS binding protein 2-like / Q93073*ENSMUSG0000003509330


Protein motifs (from Interpro)
Interpro ID Name
 IPR004038  Ribosomal protein L7Ae/L30e/S12e/Gadd45
 IPR029064  50S ribosomal protein L30e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001514 selenocysteine incorporation IMP
 biological_processGO:0021756 striatum development IMP
 biological_processGO:0048666 neuron development IMP
 biological_processGO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0003730 mRNA 3"-UTR binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035368 selenocysteine insertion sequence binding IDA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Scarb1tm1b(EUCOMM)Wtsi/Scarb1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Scarb1tm1b(EUCOMM)Wtsi/Bay

 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Scarb1tm1b(EUCOMM)Wtsi/Scarb1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Scarb1tm1b(EUCOMM)Wtsi/Bay

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: C57BL/6J

 MP:0001775 abnormal selenium level "anomalous concentration of this essential trace element, required for glutathione peroxidase and other enzymes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: C57BL/6J

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Scarb1tm1b(EUCOMM)Wtsi/Scarb1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Scarb1tm1b(EUCOMM)Wtsi/Bay

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: C57BL/6J

 MP:0005103 abnormal retinal pigmentation "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Scarb1tm1b(EUCOMM)Wtsi/Scarb1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Scarb1tm1b(EUCOMM)Wtsi/Bay

 MP:0008044 increased NK cell number "greater number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Mysm1tm1a(KOMP)Wtsi/Mysm1+
Genetic Background: Not Specified

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: C57BL/6J

Allelic Composition: Secisbp2tm1d(EUCOMM)Wtsi/Secisbp2tm1d(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0011105 partial embryonic lethality between implantation and placentation "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: C57BL/6J

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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