ENSMUSG00000035186


Mus musculus

Features
Gene ID: ENSMUSG00000035186
  
Biological name :Ubd
  
Synonyms : P63072 / Ubd / ubiquitin D
  
Possible biological names infered from orthology : O15205
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 37193892
Gene end: 37196095
  
Corresponding Affymetrix probe sets: 10445112 (MoGene1.0st)   1419762_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035808
NCBI entrez gene - 24108     See in Manteia.
MGI - MGI:1344410
RefSeq - NM_023137
RefSeq Peptide - NP_075626
swissprot - P63072
Ensembl - ENSMUSG00000035186
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UBDENSG00000213886Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR019956  Ubiquitin
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032446 protein modification by small protein conjugation IC
 biological_processGO:0034341 response to interferon-gamma IEP
 biological_processGO:0034612 response to tumor necrosis factor IEP
 biological_processGO:0043011 myeloid dendritic cell differentiation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0070842 aggresome assembly IEA
 biological_processGO:1901990 regulation of mitotic cell cycle phase transition IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016235 aggresome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0070628 proteasome binding IEA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dnmt1tm2Jae/Dnmt1tm2Jae,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6

 MP:0003945 abnormal lymphocyte physiology "abnormal function of any of the white blood cells that includes B cells, T cells, and NK cells " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Dnmt1tm2Jae/Dnmt1tm2Jae,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Dnmt1tm2Jae/Dnmt1tm2Jae,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028954 Nub1 / P54729 / negative regulator of ubiquitin-like proteins 1 / Q9Y5A7*  / complex / reaction






 

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