ENSMUSG00000035212


Mus musculus

Features
Gene ID: ENSMUSG00000035212
  
Biological name :Leprot
  
Synonyms : Leprot / Leptin receptor-related protein / O89013
  
Possible biological names infered from orthology : leptin receptor overlapping transcript / O15243
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: C6
Gene start: 101647718
Gene end: 101659364
  
Corresponding Affymetrix probe sets: 10506298 (MoGene1.0st)   1424438_a_at (Mouse Genome 430 2.0 Array)   1436900_x_at (Mouse Genome 430 2.0 Array)   1451350_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030254
Ensembl peptide - ENSMUSP00000102540
NCBI entrez gene - 230514     See in Manteia.
MGI - MGI:2687005
RefSeq - NM_175036
RefSeq Peptide - NP_778201
swissprot - O89013
Ensembl - ENSMUSG00000035212
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01026681.1ENSDARG00000115547Danio rerio
 CABZ01044235.1ENSDARG00000110105Danio rerio
 LEPROTENSGALG00000011047Gallus gallus
 LEPROTENSG00000213625Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CQ74 / Leprotl1 / Leptin receptor overlapping transcript-like 1 / O95214*ENSMUSG0000003151373


Protein motifs (from Interpro)
Interpro ID Name
 IPR007262  Vacuolar protein sorting 55


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0060400 negative regulation of growth hormone receptor signaling pathway ISO
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 biological_processGO:2000009 negative regulation of protein localization to cell surface ISO
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0011941 increased fluid intake "increase in the total amount of fluid taken in over time when compared to the normal state" [MGI:csmith]
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Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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