ENSMUSG00000035293


Mus musculus

Features
Gene ID: ENSMUSG00000035293
  
Biological name :G2e3
  
Synonyms : G2e3 / G2/M phase-specific E3 ubiquitin-protein ligase / Q5RJY2
  
Possible biological names infered from orthology : Q7L622
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: B3
Gene start: 51348061
Gene end: 51376986
  
Corresponding Affymetrix probe sets: 10395612 (MoGene1.0st)   1434699_at (Mouse Genome 430 2.0 Array)   1434700_at (Mouse Genome 430 2.0 Array)   1455355_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113270
Ensembl peptide - ENSMUSP00000054474
Ensembl peptide - ENSMUSP00000113191
NCBI entrez gene - 217558     See in Manteia.
MGI - MGI:2444298
RefSeq - NM_001015099
RefSeq - NM_001167963
RefSeq - NM_001167964
RefSeq Peptide - NP_001161436
RefSeq Peptide - NP_001015099
RefSeq Peptide - NP_001161435
swissprot - Q5RJY2
swissprot - E9Q7E5
swissprot - E9Q7C2
Ensembl - ENSMUSG00000035293
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 g2e3ENSDARG00000001313Danio rerio
 si:ch211-37e10.1ENSDARG00000055506Danio rerio
 si:ch211-57f7.7ENSDARG00000093131Danio rerio
 G2E3ENSGALG00000009907Gallus gallus
 G2E3ENSG00000092140Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phf7 / Q9DAG9 / PHD finger protein 7 / Q9BWX1*ENSMUSG0000002190216


Protein motifs (from Interpro)
Interpro ID Name
 IPR000569  HECT domain
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR034732  Extended PHD (ePHD) domain
 IPR035983  HECT, E3 ligase catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0001824 blastocyst development IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Myo5argsc940/Myo5argsc940
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Myo5argsc940/Myo5argsc940
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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