ENSMUSG00000035578


Mus musculus

Features
Gene ID: ENSMUSG00000035578
  
Biological name :Iqcg
  
Synonyms : Iqcg / IQ domain-containing protein G / Q80W32
  
Possible biological names infered from orthology : IQ motif containing G / Q9H095
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B3
Gene start: 33015385
Gene end: 33056218
  
Corresponding Affymetrix probe sets: 10439114 (MoGene1.0st)   1460467_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041686
Ensembl peptide - ENSMUSP00000110752
NCBI entrez gene - 69707     See in Manteia.
MGI - MGI:1916957
RefSeq - XM_011246004
RefSeq - NM_178378
RefSeq - XM_006522519
RefSeq - XM_006522520
RefSeq Peptide - NP_848465
swissprot - F8WHQ8
swissprot - Q80W32
Ensembl - ENSMUSG00000035578
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 iqcgENSDARG00000068678Danio rerio
 IQCGENSGALG00000007607Gallus gallus
 IQCGENSG00000114473Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007286 spermatid development IMP
 biological_processGO:0007288 sperm axoneme assembly IMP
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0002177 manchette IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0031514 motile cilium IDA
 cellular_componentGO:0036126 sperm flagellum IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding ISO
 molecular_functionGO:0030544 Hsp70 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0001932 abnormal spermiogenesis "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid5btm1Whit/Arid5btm1Whit
Genetic Background: B6.129S1-Arid5btm1Whit

Allelic Composition: Iqcgesgd12d/Iqcgtm1b(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N * FVB/NJ

Allelic Composition: Iqcgtm1b(EUCOMM)Wtsi/Iqcgtm1b(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6N * FVB/NJ

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Iqcgesgd12d/Iqcgesgd12d
Genetic Background: involves: C57BL/6

Allelic Composition: Iqcgesgd12d/Iqcgtm1b(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N * FVB/NJ

Allelic Composition: Iqcgtm1b(EUCOMM)Wtsi/Iqcgtm1b(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6N * FVB/NJ

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
Show

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0008545 absent sperm flagella "mature spermatozoa lack a flagella" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0009239 short sperm flagellum "decreased length of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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