ENSMUSG00000035686


Mus musculus

Features
Gene ID: ENSMUSG00000035686
  
Biological name :Thrsp
  
Synonyms : Q62264 / Thrsp / thyroid hormone responsive
  
Possible biological names infered from orthology : Q92748
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E1
Gene start: 97412938
Gene end: 97417730
  
Corresponding Affymetrix probe sets: 10565609 (MoGene1.0st)   1422973_a_at (Mouse Genome 430 2.0 Array)   1424737_at (Mouse Genome 430 2.0 Array)   1444166_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042988
NCBI entrez gene - 21835     See in Manteia.
MGI - MGI:109126
RefSeq - NM_009381
RefSeq Peptide - NP_033407
swissprot - Q543J4
swissprot - Q62264
Ensembl - ENSMUSG00000035686
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000042944Gallus gallus
 THRSPENSGALG00000035803Gallus gallus
 THRSPENSG00000151365Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CQ20 / Mid1ip1 / Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) / Q9NPA3* / MID1 interacting protein 1*ENSMUSG0000000803535


Protein motifs (from Interpro)
Interpro ID Name
 IPR009786  Spot 14 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0010866 regulation of triglyceride biosynthetic process IMP
 biological_processGO:0046890 regulation of lipid biosynthetic process IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
Import of palmitoyl-CoA into the mitochondrial matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001882 abnormal lactation "atypical production of milk from the mammary gland" [J:51296]
Show

Allelic Composition: Actbtm1Npa/Actbtm1Npa
Genetic Background: involves: BALB/cJ

 MP:0002118 abnormal lipid homeostasis "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Actbtm1Npa/Actbtm1Npa
Genetic Background: involves: BALB/cJ

 MP:0004047 abnormal milk composition "anomaly in the protein or lipid content of milk" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Actbtm1Npa/Actbtm1Npa
Genetic Background: involves: BALB/cJ

 MP:0005318 decreased triglyceride level "lower than normal concentration of triacylglycerols " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Actbtm1Npa/Actbtm1Npa
Genetic Background: involves: BALB/cJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000008035 Q9CQ20 / Mid1ip1 / Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) / Q9NPA3* / MID1 interacting protein 1*  / complex / reaction






 

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