ENSMUSG00000035765


Mus musculus

Features
Gene ID: ENSMUSG00000035765
  
Biological name :Dym
  
Synonyms : Dym / Dymeclin / Q8CHY3
  
Possible biological names infered from orthology : Q7RTS9
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: E2
Gene start: 75018772
Gene end: 75286966
  
Corresponding Affymetrix probe sets: 10456727 (MoGene1.0st)   1423736_a_at (Mouse Genome 430 2.0 Array)   1430532_at (Mouse Genome 430 2.0 Array)   1437141_x_at (Mouse Genome 430 2.0 Array)   1441008_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047054
NCBI entrez gene - 69190     See in Manteia.
MGI - MGI:1918480
RefSeq - XM_006526219
RefSeq - NM_027727
RefSeq - XM_006526217
RefSeq - XM_006526218
RefSeq - XM_006526216
RefSeq Peptide - NP_082003
swissprot - Q8CHY3
Ensembl - ENSMUSG00000035765
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dymENSDARG00000042555Danio rerio
 DYMENSGALG00000037426Gallus gallus
 DYMENSG00000141627Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR019142  Dymeclin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0060348 bone development IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000120 malocclusion "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0000165 abnormal hypertrophic chondrocyte zone "anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0000166 abnormal chondrocyte morphology "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0002114 abnormal axial skeleton morphology "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0002115 abnormal skeleton extremities morphology "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0003055 abnormal epiphyseal plate morphology "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0003109 short femur "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0003409 decreased width of hypertrophic chondrocyte zone "decreased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0003587 ureter obstruction "any impediment, blockage, or reversal of the normal flow of the urine towards the bladder" [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0004174 abnormal spine curvature "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0004351 short humerus "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0004610 small vertebrae "reduced size of the bony segments of the spinal column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0004672 short ribs "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0005352 small skull "less than the normal size of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0006397 disorganized long bone epiphyseal plate "a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0006399 abnormal long bone epiphyseal ossification zone morphology "any anomaly in the structure of the layer of the epiphyseal plate where new bone matrix is deposited" [CALnet tutorial:http://137.222.110.150/calnet/Introanat/Introanat.htm, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0008526 decreased skull width "having a decreased side-to-side distance of the skull" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0008546 abnormal vesicle-mediated transport "anomaly in the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell" [GO:0016192]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0011862 decreased cranium length "having an decreased dorsal-to-ventral distance of the cranium" [MGI:mnk]
Show

Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Alb1-cre)7Gsc/0
Genetic Background: involves: 129S2/SvPas * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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