ENSMUSG00000035778


Mus musculus

Features
Gene ID: ENSMUSG00000035778
  
Biological name :Ggta1
  
Synonyms : Ggta1 / N-acetyllactosaminide alpha-1,3-galactosyltransferase / P23336
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: B
Gene start: 35400179
Gene end: 35463231
  
Corresponding Affymetrix probe sets: 10482059 (MoGene1.0st)   1418483_a_at (Mouse Genome 430 2.0 Array)   1451843_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000132408
Ensembl peptide - ENSMUSP00000108626
Ensembl peptide - ENSMUSP00000115112
Ensembl peptide - ENSMUSP00000049408
Ensembl peptide - ENSMUSP00000078393
Ensembl peptide - ENSMUSP00000099858
Ensembl peptide - ENSMUSP00000108625
NCBI entrez gene - 14594     See in Manteia.
MGI - MGI:95704
RefSeq - XM_011239029
RefSeq - NM_001145821
RefSeq - NM_001308299
RefSeq - NM_001308300
RefSeq - NM_010283
RefSeq - XM_011239026
RefSeq - XM_011239027
RefSeq - XM_011239028
RefSeq Peptide - NP_034413
RefSeq Peptide - NP_001139293
RefSeq Peptide - NP_001295228
RefSeq Peptide - NP_001295229
swissprot - Q91W00
swissprot - Q9DBU1
swissprot - B2FDI6
swissprot - P23336
swissprot - Q3TXW0
swissprot - Q8C2H7
Ensembl - ENSMUSG00000035778
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
4930402F06Rik / RIKEN cDNA 4930402F06 geneENSMUSG0000007942142
A2AUQ7 / 4930568D16Rik / N-acetyllactosaminide alpha-1,3-galactosyltransferase-like 1 ENSMUSG0000002688236
Glt6d1 / Q2NKH9 / Glycosyltransferase 6 domain-containing protein 1 / Q7Z4J2* / glycosyltransferase 6 domain containing 1*ENSMUSG0000003640135
Q3V1N9 / A3galt2 / alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase) / U3KPV4* / alpha 1,3-galactosyltransferase 2*ENSMUSG0000002879435
Abo / P38649 / Histo-blood group ABO system transferase / ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase*ENSMUSG0000001578733
Gbgt1 / Q8VI38 / Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 / Q8N5D6* / globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)*ENSMUSG0000002682931


Protein motifs (from Interpro)
Interpro ID Name
 IPR005076  Glycosyl transferase, family 6
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0009247 glycolipid biosynthetic process IBA
 biological_processGO:0030259 lipid glycosylation IBA
 biological_processGO:0033580 protein galactosylation at cell surface IDA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031982 vesicle IBA
 cellular_componentGO:0031985 Golgi cisterna ISS
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IBA
 molecular_functionGO:0016758 transferase activity, transferring hexosyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001800 abnormal humoral immune response "abnormal immune function mediated by antibodies" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Pdgfrbtm4Sor/Pdgfrbtm4Sor
Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)

Allelic Composition: Cr2tm1Crr/Cr2tm1Crr,Ggta1tm1Jbl/Ggta1tm1Jbl
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0001805 decreased IgG "less than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pdgfrbtm4Sor/Pdgfrbtm4Sor
Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0002459 abnormal B cell physiology "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Lystbg-2Btlr/Lystbg-2Btlr
Genetic Background: C57BL/6J-Lystbg-2Btlr

 MP:0002490 abnormal circulating immunoglobulin concentration "deviation from the normal levels of glycoproteins present in the blood and other tissue, often functioning as antibodies" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pdgfrbtm4Sor/Pdgfrbtm4Sor
Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)

 MP:0002494 increased IgM "greater than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pdgfrbtm4Sor/Pdgfrbtm4Sor
Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)

 MP:0004942 abnormal B cell selection "anomaly in the process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival" [GO:0002339]
Show

Allelic Composition: Lystbg-2Btlr/Lystbg-2Btlr
Genetic Background: C57BL/6J-Lystbg-2Btlr

 MP:0005671 response to transplant "the body s reaction to the grafting of organs, tissues, or cells taken from the same individual for another area of the body or from another individual" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:52834]
Show

Allelic Composition: Pdgfrbtm4Sor/Pdgfrbtm4Sor
Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)

 MP:0008211 decreased mature B cell number "reduced number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149]
Show

Allelic Composition: Lystbg-Btlr/Lystbg-Btlr
Genetic Background: C57BL/6J-Lystbg-Btlr

Allelic Composition: Ggta1tm1Jbl/Ggta1+,Ightm1Jiac/Igh+,Igktm1Jiac/Igktm1Jiac
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Ggta1tm1Jbl/Ggta1+,Ightm1Jiac/Ightm1Jiac,Igktm1Jiac/Igktm1Jiac
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0010267 decreased lung tumor incidence "less than the expected number of neoplams in the lung, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pdgfrbtm4Sor/Pdgfrbtm4Sor
Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr