ENSMUSG00000036026


Mus musculus

Features
Gene ID: ENSMUSG00000036026
  
Biological name :Tmem63b
  
Synonyms : Q3TWI9 / Tmem63b / transmembrane protein 63b
  
Possible biological names infered from orthology : Q5T3F8
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B3
Gene start: 45660171
Gene end: 45686905
  
Corresponding Affymetrix probe sets: 10451167 (MoGene1.0st)   10451193 (MoGene1.0st)   1445464_at (Mouse Genome 430 2.0 Array)   1452219_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109151
Ensembl peptide - ENSMUSP00000121681
Ensembl peptide - ENSMUSP00000120579
Ensembl peptide - ENSMUSP00000118838
Ensembl peptide - ENSMUSP00000118826
Ensembl peptide - ENSMUSP00000115408
NCBI entrez gene - 224807     See in Manteia.
MGI - MGI:2387609
RefSeq - XM_006524140
RefSeq - XM_006524139
RefSeq - XM_006524136
RefSeq - XM_006524137
RefSeq - NM_198167
RefSeq - XM_006524138
RefSeq Peptide - NP_937810
swissprot - Q3TWI9
swissprot - D3Z2D8
swissprot - D3YXV7
swissprot - D3YY83
swissprot - D3YYJ8
swissprot - D3Z0P2
Ensembl - ENSMUSG00000036026
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem63baENSDARG00000104559Danio rerio
 tmem63bbENSDARG00000106631Danio rerio
 zgc:153431ENSDARG00000103608Danio rerio
 TMEM63BENSGALG00000010282Gallus gallus
 Q5T3F8ENSG00000137216Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91YT8 / Tmem63a / transmembrane protein 63a / O94886*ENSMUSG0000002651953
Q8CBX0 / Tmem63c / transmembrane protein 63c / Q9P1W3*ENSMUSG0000003414541


Protein motifs (from Interpro)
Interpro ID Name
 IPR003864  Calcium-dependent channel, 7TM region, putative phosphate
 IPR027815  10TM putative phosphate transporter, cytosolic domain
 IPR032880  Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Thratm1b(EUCOMM)Wtsi/Thra+
Genetic Background: C57BL/6N-Thratm1b(EUCOMM)Wtsi/Ics

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Thratm1b(EUCOMM)Wtsi/Thra+
Genetic Background: C57BL/6N-Thratm1b(EUCOMM)Wtsi/Ics

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Thratm1b(EUCOMM)Wtsi/Thra+
Genetic Background: C57BL/6N-Thratm1b(EUCOMM)Wtsi/Ics

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Thratm1b(EUCOMM)Wtsi/Thra+
Genetic Background: C57BL/6N-Thratm1b(EUCOMM)Wtsi/Ics

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Thratm1b(EUCOMM)Wtsi/Thra+
Genetic Background: C57BL/6N-Thratm1b(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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