ENSMUSG00000036036


Mus musculus

Features
Gene ID: ENSMUSG00000036036
  
Biological name :Zfp57
  
Synonyms : Q8C6P8 / Zfp57 / zinc finger protein 57
  
Possible biological names infered from orthology : Q9NU63 / ZFP57 zinc finger protein
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 37001163
Gene end: 37010635
  
Corresponding Affymetrix probe sets: 10445071 (MoGene1.0st)   1450929_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135655
Ensembl peptide - ENSMUSP00000065811
Ensembl peptide - ENSMUSP00000087414
Ensembl peptide - ENSMUSP00000133460
Ensembl peptide - ENSMUSP00000133582
Ensembl peptide - ENSMUSP00000133821
Ensembl peptide - ENSMUSP00000133894
Ensembl peptide - ENSMUSP00000134024
Ensembl peptide - ENSMUSP00000134116
Ensembl peptide - ENSMUSP00000134418
NCBI entrez gene - 22715     See in Manteia.
MGI - MGI:99204
RefSeq - XM_017317459
RefSeq - NM_001013745
RefSeq - NM_001168501
RefSeq - NM_001168502
RefSeq - XM_006524224
RefSeq - XM_017317458
RefSeq Peptide - NP_001013767
RefSeq Peptide - NP_001161973
RefSeq Peptide - NP_001161974
swissprot - G3UY05
swissprot - G3UYC1
swissprot - G3UYK1
swissprot - H3BL53
swissprot - G3UX77
swissprot - Q8C6P8
swissprot - G3UWX4
Ensembl - ENSMUSG00000036036
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ZFP57ENSG00000204644Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006349 regulation of gene expression by genetic imprinting ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0043045 DNA methylation involved in embryo development IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005720 nuclear heterochromatin IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003718 maternal effect "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Plpp3tm2Stw/Plpp3tm2Stw
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Tg(Zp3-cre)93Knw/0,Zfp57tm1Xjli/Zfp57tm1Xjli
Genetic Background: either: (involves: 129S6/SvEvTac * C57BL/6J) or (involves: 129S6/SvEvTac * Black Swiss * C57BL/6J)

 MP:0003787 abnormal imprinting "defect in the normal inactivation of specific loci during gametogenesis" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Plpp3tm2Stw/Plpp3tm2Stw
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Plpp3tm2Stw/Plpp3tm2Stw
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Plpp3tm2Stw/Plpp3tm2Stw
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Tg(Zp3-cre)93Knw/0,Zfp57tm1Xjli/Zfp57tm1Xjli
Genetic Background: either: (involves: 129S6/SvEvTac * C57BL/6J) or (involves: 129S6/SvEvTac * Black Swiss * C57BL/6J)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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