ENSMUSG00000036099


Mus musculus

Features
Gene ID: ENSMUSG00000036099
  
Biological name :Vezt
  
Synonyms : Q3ZK22 / vezatin, adherens junctions transmembrane protein / Vezt
  
Possible biological names infered from orthology : Q9HBM0
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C2
Gene start: 93939165
Gene end: 94035817
  
Corresponding Affymetrix probe sets: 10372003 (MoGene1.0st)   10372005 (MoGene1.0st)   1438197_at (Mouse Genome 430 2.0 Array)   1438881_at (Mouse Genome 430 2.0 Array)   1441124_at (Mouse Genome 430 2.0 Array)   1455472_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123575
Ensembl peptide - ENSMUSP00000121727
Ensembl peptide - ENSMUSP00000122561
Ensembl peptide - ENSMUSP00000113715
Ensembl peptide - ENSMUSP00000113321
Ensembl peptide - ENSMUSP00000037955
Ensembl peptide - ENSMUSP00000113983
Ensembl peptide - ENSMUSP00000114550
Ensembl peptide - ENSMUSP00000121105
NCBI entrez gene - 215008     See in Manteia.
MGI - MGI:2143698
RefSeq - NM_001304720
RefSeq - NM_001304572
RefSeq - NM_001304575
RefSeq - NM_172538
RefSeq Peptide - NP_001291501
RefSeq Peptide - NP_766126
RefSeq Peptide - NP_001291649
RefSeq Peptide - NP_001291504
swissprot - Q3ZK22
swissprot - D3YVB1
swissprot - D3Z4E6
swissprot - F6TIK3
swissprot - F6W383
swissprot - F7CPT8
Ensembl - ENSMUSG00000036099
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 veztENSDARG00000075215Danio rerio
 VEZTENSGALG00000011357Gallus gallus
 VEZTENSG00000028203Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026858  Vezatin
 IPR026859  Myosin-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0002142 stereocilia ankle link complex IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017022 myosin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Usp3tm1b(EUCOMM)Wtsi/Usp3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Usp3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0001728 failure of implantation "inability of the blastocyst to attach to the endometrium of the uterus" [J:38772]
Show

Allelic Composition: Itktm1Litt/Itktm1Litt,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C3H * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pyytm1Mws/Pyytm1Mws
Genetic Background: involves: C57BL/6J

Allelic Composition: Vezttm1.1Smc/Vezt+
Genetic Background: either: (involves: 129S2/SvPas * BALB/c * C57BL/6 * MF1) or (involves: 129S2/SvPas * BALB/c * C57BL/6 * C57BL/6N * MF1)

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Usp3tm1b(EUCOMM)Wtsi/Usp3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Usp3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Itktm1Litt/Itktm1Litt,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C3H * C57BL/6J

 MP:0003694 failure to hatch from the zona pellucida "the embryo fails to break out of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, may be seen in vivo or in cultured embryos" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Itktm1Litt/Itktm1Litt,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C3H * C57BL/6J

 MP:0003695 delayed hatching from the zona pellucida "the embryo takes longer than normal to break out of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, may be seen in vivo or in cultured embryos" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Itktm1Litt/Itktm1Litt,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C3H * C57BL/6J

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Usp3tm1b(EUCOMM)Wtsi/Usp3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Usp3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Usp3tm1b(EUCOMM)Wtsi/Usp3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Usp3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0011093 complete embryonic lethality at implantation "death of all organisms of a given genotype in a population at the point of implantation (Mus: E4.5)" [MGI:csmith]
Show

Allelic Composition: Itktm1Litt/Itktm1Litt,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C3H * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Usp3tm1b(EUCOMM)Wtsi/Usp3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Usp3tm1b(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr