ENSMUSG00000036208


Mus musculus

Features
Gene ID: ENSMUSG00000036208
  
Biological name :Nepro
  
Synonyms : Nepro / Nucleolus and neural progenitor protein / Q8R2U2
  
Possible biological names infered from orthology : Q6NW34
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B4
Gene start: 44724301
Gene end: 44737284
  
Corresponding Affymetrix probe sets: 10435897 (MoGene1.0st)   1451439_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038779
Ensembl peptide - ENSMUSP00000116115
Ensembl peptide - ENSMUSP00000122052
Ensembl peptide - ENSMUSP00000122861
NCBI entrez gene - 212547     See in Manteia.
MGI - MGI:2384836
RefSeq - XM_006521972
RefSeq - NM_145972
RefSeq - XM_006521971
RefSeq Peptide - NP_666084
swissprot - Q8R2U2
swissprot - F6RAK6
swissprot - D6RFS8
Ensembl - ENSMUSG00000036208
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neproENSDARG00000043566Danio rerio
 NEPROENSGALG00000015182Gallus gallus
 NEPROENSG00000163608Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR027951  Domain of unknown function DUF4477


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IDA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003111 abnormal nucleus morphology "abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Dph1tm2Bhr/Dph1+,Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+,Mesp1tm2(cre)Ysa/Mesp1+
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0008830 abnormal nucleolus morphology "any structural anomaly of the small rounded nuclear substructure that produces ribonucleoprotein" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Dph1tm2Bhr/Dph1+,Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+,Mesp1tm2(cre)Ysa/Mesp1+
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Dph1tm2Bhr/Dph1+,Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+,Mesp1tm2(cre)Ysa/Mesp1+
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

Allelic Composition: Neprotm1.1Tets/Neprotm1.1Tets
Genetic Background: B6JJcl.129(Cg)-Neprotm1.1Tets

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0012129 failure of blastocyst formation "inability to form a blastocyst from a solid ball of cells known as a morula" [MGI:anna]
Show

Allelic Composition: Dph1tm2Bhr/Dph1+,Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+,Mesp1tm2(cre)Ysa/Mesp1+
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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