ENSMUSG00000036285


Mus musculus

Features
Gene ID: ENSMUSG00000036285
  
Biological name :Noa1
  
Synonyms : Nitric oxide-associated protein 1 / Noa1 / Q9JJG9
  
Possible biological names infered from orthology : nitric oxide associated 1 / Q8NC60
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: C3.3
Gene start: 77294182
Gene end: 77310084
  
Corresponding Affymetrix probe sets: 10530832 (MoGene1.0st)   1418222_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045948
NCBI entrez gene - 56412     See in Manteia.
MGI - MGI:1914306
RefSeq - NM_019836
RefSeq - XM_006535153
RefSeq Peptide - NP_062810
swissprot - Q9JJG9
Ensembl - ENSMUSG00000036285
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 noa1ENSDARG00000102934Danio rerio
 NOA1ENSGALG00000038585Gallus gallus
 NOA1ENSG00000084092Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006073  GTP binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030378  Circularly permuted (CP)-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010941 regulation of cell death IEA
 biological_processGO:0032543 mitochondrial translation IMP
 biological_processGO:0042254 ribosome biogenesis IBA
 biological_processGO:0043457 regulation of cellular respiration IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031314 extrinsic component of mitochondrial inner membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0005031 abnormal trophoblast "malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0006035 abnormal mitochondrial morphology "anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0006036 abnormal mitochondrial physiology 
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0006043 decreased apoptosis "less than normal cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0008944 decreased sensitivity to induced cell death "increase in the exposure level to an agent that is required to induce cessation of function at the cellular level" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0011635 abnormal mitochondrial crista morphology "Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0013241 embryo tissue necrosis "morphological changes resulting from pathological death of some or all embryo tissue; usually due to irreversible damage" [MGI:csmith]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

 MP:0013505 decreased embryonic tissue cell apoptosis "decrease in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
Show

Allelic Composition: Srebf2Gt(YTA054)Byg/Srebf2lop13
Genetic Background: involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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