ENSMUSG00000036403


Mus musculus

Features
Gene ID: ENSMUSG00000036403
  
Biological name :Cep135
  
Synonyms : Centrosomal protein of 135 kDa / Cep135 / Q6P5D4
  
Possible biological names infered from orthology : centrosomal protein 135 / Q66GS9
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: C3.3
Gene start: 76588698
Gene end: 76646466
  
Corresponding Affymetrix probe sets: 10522627 (MoGene1.0st)   1444201_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038674
Ensembl peptide - ENSMUSP00000112602
NCBI entrez gene - 381644     See in Manteia.
MGI - MGI:2681869
RefSeq - XM_006535028
RefSeq - NM_199032
RefSeq - XM_006535026
RefSeq - XM_006535027
RefSeq - XM_006535023
RefSeq - XM_006535025
RefSeq Peptide - NP_950197
swissprot - Q6P5D4
Ensembl - ENSMUSG00000036403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cep135ENSDARG00000002991Danio rerio
 CEP135ENSGALG00000013776Gallus gallus
 CEP135ENSG00000174799Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6NY15 / Tsga10 / testis specific 10 / Q9BZW7*ENSMUSG0000006077123


Protein motifs (from Interpro)
Interpro ID Name
 IPR026732  Centrosomal protein of 135kDa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007099 centriole replication ISO
 biological_processGO:0010457 centriole-centriole cohesion ISO
 biological_processGO:1902857 positive regulation of non-motile cilium assembly ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0008022 protein C-terminus binding ISO


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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