| MP:0000048 | abnormal stria vascularis | "anomalous structure of the layer of highly vascularized pigmented granular cells on the outer wall of the cochlear duct" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
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| MP:0000371 | diluted coat color | "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/Mcoln3Va-J
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: B6C3Fe-a/a Hoxa13Hd Mcoln3Va-J/J
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| MP:0000373 | belly spot | "the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Casp8tm1Hed/Casp8tm1Hed,Cd19tm1(cre)Cgn/Cd19+
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: B6C3Fe-a/a Hoxa13Hd Mcoln3Va-J/J
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| MP:0000421 | mottled coat | "coat has spots, streaks, and/or blotches of a different color" [J:17194] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/Mcoln3Va-J
Genetic Background: B6C3Fe-a/a Hoxa13Hd Mcoln3Va-J/J
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Mcoln3Va-J/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0001386 | abnormal maternal nurturing | "failure of mothers to tend offspring" [J:39801] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
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| MP:0001394 | circling | "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
Allelic Composition: Mcoln3Va/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0001399 | hyperactivity | "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
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| MP:0001401 | jumpy | "marked by fitful, jerky movements" [J:22295] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
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| MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001408 | stereotypic behavior | "repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s wrong with my mouse?:ISBN 0-471-31639-3] |
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Allelic Composition: Mcoln3Va-J/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0001522 | impaired swimming | "reduced ability or inability to swim" [J:45446, J:39081] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0001523 | impaired righting response | "reduced ability or greater amount of time needed to recover from supine position" [J:25565] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
Allelic Composition: Mcoln3Va/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0001967 | deafness | "inability to hear" [J:57651] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/Mcoln3Va-J
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0002622 | abnormal cochlear hair cell morphology | "malformation of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0002826 | tonic seizures | "increased number or decreased threshold for the induction of a seizure characterized by muscle rigidity" [hdene:Howard Dene , Mouse Genome Informatics Curator] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
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| MP:0002856 | abnormal vestibular ganglion morphology | "malformation of the group of neurons associated with the vestibular part of the eighth cranial nerve that are involved in equilibration" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
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| MP:0002857 | cochlear ganglion degeneration | "loss of neural cell bodies in the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
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| MP:0002938 | white spotting | "the appearance of patches of white fur" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/Mcoln3Va-J
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0002939 | head spot | "the appearance of a round area of white fur on the head" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: B6C3Fe-a/a Hoxa13Hd Mcoln3Va-J/J
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| MP:0003150 | detached tectorial membrane | "tectorial membrane is abnormally detached from the cochlear epithelium or spiral limbus" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:77634] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
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| MP:0003312 | abnormal locomotor coordination | "reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
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| MP:0003703 | abnormal vestibulocochlear ganglion morphology | "malformed group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
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| MP:0004249 | abnormal crista ampullaris morphology | "anomaly in the elevation found on the inner surface of the ampullae of each semicircular duct; filaments of the vestibular nerve pass through the crista to reach hair cells on its surface; the hair cells are capped by the cupula, a gelatinous protein-polysaccharide mass" [J:60193, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
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| MP:0004362 | cochlear hair cell degeneration | "degeneration or loss of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
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| MP:0004591 | enlarged tectorial membrane | "increased size of the overlaying membrane of cochlear duct, an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trpa1tm1Jul/Trpa1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
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| MP:0005175 | non-pigmented tail tip | "lack of color at the end of the tail " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
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Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: Not Specified
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| MP:0005307 | head tossing | "compulsive flailing of the head in multiple directions" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
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| MP:0005366 | variegated coat color | "dappled coloration of the fur; mosaic" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/Mcoln3Va-J
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0009379 | abnormal foot pigmentation | "anomaly in the coloration of the foot" [MGI:mberry "Melissa Berry, Genetics Resources Curator"] |
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Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: Not Specified
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| MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR
Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: mixed
Allelic Composition: Mcoln3Va-J/Mcoln3Va-J
Genetic Background: B6.Cg-Mcoln3Va-J
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| MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Mcoln3Va/Mcoln3Va-J
Genetic Background: Not Specified
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| MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
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Allelic Composition: Otx2tm1.1Tlam/Otx2tm2(cre/ERT2)Tlam
Genetic Background: Not Specified
Allelic Composition: Mcoln3Va-J/?
Genetic Background: involves: C3HeB/FeJLe * C57BL/6J
Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: B6C3Fe-a/a Hoxa13Hd Mcoln3Va-J/J
Allelic Composition: Mcoln3Va-J/?
Genetic Background: involves: A/J * C57BL/6J
Allelic Composition: Mcoln3Va-J/?
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mcoln3Va-J/?
Genetic Background: involves: BALB/cByJ * C57BL/6J
Allelic Composition: Mcoln3Va-J/?
Genetic Background: involves: C57BL/6J * CZECHII/EiJ
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