Manteia - Molecule gene

ENSMUSG00000036955

Mus musculus

Features

Gene ID:	ENSMUSG00000036955

Biological name :	Kif1bp

Synonyms :	KIF1-binding protein / Kif1bp / Q6ZPU9

Possible biological names infered from orthology :	Q96EK5

Species:	Mus musculus

Chr. number:	10
Strand:	-1
Band:	B4
Gene start:	62538626
Gene end:	62578457

Corresponding Affymetrix probe sets:	10369620 (MoGene1.0st) 1432593_at (Mouse Genome 430 2.0 Array) 1452874_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000125162 Ensembl peptide - ENSMUSP00000134770 Ensembl peptide - ENSMUSP00000125236 Ensembl peptide - ENSMUSP00000065160 Ensembl peptide - ENSMUSP00000125070 NCBI entrez gene - 72320 See in Manteia. MGI - MGI:1919570 RefSeq - XM_006514192 RefSeq - NM_028197 RefSeq Peptide - NP_082473 swissprot - H3BIY2 swissprot - E0CXJ9 swissprot - E0CXN7 swissprot - Q6ZPU9 swissprot - F7DEX6 Ensembl - ENSMUSG00000036955

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
kif1bp	ENSDARG00000062053	Danio rerio
KIF1BP	ENSGALG00000004156	Gallus gallus
KIF1BP	ENSG00000198954	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

ID

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR011990	Tetratricopeptide-like helical domain superfamily
IPR022083	KIF-1 binding protein

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006839	mitochondrial transport	IEA
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0007399	nervous system development	IEA
biological_process	GO:0030154	cell differentiation	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005739	mitochondrion	IEA
cellular_component	GO:0005856	cytoskeleton	IEA
molecular_function	GO:0005515	protein binding	IEA
molecular_function	GO:0019894	kinesin binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000111	cleft palate	"congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0000602	enlarged sinusoidal spaces	"larger than normal sized cavities in the liver " [J:23170]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0000788	abnormal cerebral cortex morphology	"malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0001015	small superior cervical ganglion	"reduced size of the group of neurons that is the largest of the ganglia of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [J:23882]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0001093	small trigeminal ganglion	"reduced size of the trigeminal ganglion" [J:25565, J:17123]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0001575	cyanosis	"a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0001672	abnormal embryogenesis/ development	"anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified Allelic Composition: Kif1bp^em1Hmy/Kif1bp^em1Hmy,Ret^tm1Jmi/Ret^tm1Jmi Genetic Background: involves: 129X1/SvJ Allelic Composition: Kif1bp^em1Hmy/Kif1bp^em1Hmy,Ret^tm1Jmi/Ret⁺ Genetic Background: involves: 129X1/SvJ
MP:0001954	respiratory distress	"physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0002175	low brain weight	"lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0003595	epididymal cyst	"benign growths present in the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0003686	abnormal eye muscle morphology	"malformation of the muscles of the eye" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0003826	abnormal Mullerian duct morphology	"malformation of the transient embryonic tubes that empty into the cloaca and in the female develop into the oviducts, uterus, and vagina" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0004163	abnormal adenophysis morphology	"any malformation or absence of the anterior part of the pituitary that secretes a variety of hormones; its function is regulated by the hypothalamus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0008226	decreased anterior commissure size	"reduced size of a round bundle of nerve fibers that crosses the midline of the brain near the anterior limit of the third ventricle" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0009946	abnormal olfactory bulb layer morphology	"any structural anomaly of the laminar structure of the forebrain region that coordinates neuronal signaling involved in the perception of smell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0010059	olfactory bulb hypoplasia	"underdevelopment or reduced size, usually due to a reduced number of cells, of the forebrain region that coordinates neuronal signaling involved in the perception of smell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0011087	complete neonatal lethality	"death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0013001	abnormal enteric neural crest cell morphology	" any structural anomaly of the neural crest cells that arise predominantly from the vagal region of the neural tube (vagal neural crest), adjacent to somites 1-7 and migrate rostro-caudally along the gastrointestinal tract to form two ganglionated plexuses of neurons and glial cells that comprise the enteric nervous system (ENS); a smaller proportion of ENCCs come from the sacral neural crest, caudal to somite 28, and migrate caudo-rostrally to colonize the distal gut; neural crest cells are termed enteric neural crest-derived cells upon entering the foregut at E9-9.5 in mice (after 4 weeks gestation in humans)" [MGI:anna, PMID:17514199]	Show Allelic Composition: Scn1a^tm1.1Kzy/Scn1a⁺ Genetic Background: involves: 129P2/OlaHsd * C3HeB/FeJ Allelic Composition: Kif1bp^em2Hmy/Kif1bp^em2Hmy Genetic Background: Not Specified
MP:0013832	thin vagus nerve	"slender appearance of the autonomic, sensory and motor axons of the tenth cranial nerve" [ISBN:0838580343]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0013834	thin hypoglossal nerve	"slender appearance of the motor nerve which innervates all the intrinsic and all but one of the extrinsic muscles of the tongue" [ISBN:0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0013835	absent hypoglossal nerve	"absence of the motor nerve which innervates all the intrinsic and all but one of the extrinsic muscles of the tongue" [ISBN:0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0013848	subcutaneous edema	"accumulation of watery or serous fluid in the subcutaneous region below the skin" [MGI:csmith]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0013873	abnormal ductus venosus morphology	"any structural anomaly of the embryonic connection between the portal vein and inferior vena cava formed by the left umbilical vein that allows oxygenated blood to bypass the developing liver during the time when this connection is normally open; this normally closes during develpment to adulthood" [MGI:csmith]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0013874	abnormal ductus venosus topology	"aberrant position or orientation of the embryonic connection between the portal vein and inferior vena cava formed by the left umbilical vein that allows oxygenated blood to bypass the developing liver during the time when this connection is normally open; this normally closes during develpment to adulthood" [MGI:csmith]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0013875	trigeminal neuroma		Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0013971	blood in lymph vessels		Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0014002	absent extracranial vertebral artery segment		Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0014006	absent posterior communicating artery		Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0014018	embryo tumor	"presence of an unspecified tumor or aberrant growth in a prenatal orgnaism" [MGI:csmith]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/0,Picalm^tm1.1Tmae/Picalm^tm1.1Tmae Genetic Background: involves: 129 * C57BL/6 * SJL

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr