ENSMUSG00000037221


Mus musculus

Features
Gene ID: ENSMUSG00000037221
  
Biological name :Mospd3
  
Synonyms : Mospd3 / Motile sperm domain-containing protein 3 / Q8BGG6
  
Possible biological names infered from orthology : motile sperm domain containing 3 / O75425
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 137596645
Gene end: 137601058
  
Corresponding Affymetrix probe sets: 10534854 (MoGene1.0st)   1453961_a_at (Mouse Genome 430 2.0 Array)   1460452_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122462
Ensembl peptide - ENSMUSP00000040828
Ensembl peptide - ENSMUSP00000106636
Ensembl peptide - ENSMUSP00000116851
NCBI entrez gene - 68929     See in Manteia.
MGI - MGI:1916179
RefSeq - XM_006504614
RefSeq - NM_001254762
RefSeq - NM_030037
RefSeq - XM_006504612
RefSeq - XM_006504613
RefSeq Peptide - NP_084313
RefSeq Peptide - NP_001241691
swissprot - Q05DT5
swissprot - D3Z5Y3
swissprot - Q8BGG6
swissprot - D3Z1F3
Ensembl - ENSMUSG00000037221
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MOSPD3ENSG00000106330Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mospd1 / Q8VEL0 / Motile sperm domain-containing protein 1 / Q9UJG1* / motile sperm domain containing 1*ENSMUSG0000002307434


Protein motifs (from Interpro)
Interpro ID Name
 IPR000535  Major sperm protein (MSP) domain
 IPR008962  PapD-like superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016763  Vesicle-associated membrane-protein-associated protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007507 heart development IMP
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000279 ventricular hypoplasia "reduction in cell number of one or both of the two lower chambers of the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61790]
Show

Allelic Composition: Mettm3Kln/Mettm3Kln
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
Show

Allelic Composition: Mettm3Kln/Mettm3Kln
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

 MP:0000295 poorly developed ventricular trabeculae "retarded differentation of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [J:29971]
Show

Allelic Composition: Mettm3Kln/Mettm3Kln
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

 MP:0000486 abnormal pulmonary trunk morphology "structural anomaly of the region of the pulmonary artery that arises from the right ventricle to the division of the right and left pulmonary artery" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mettm3Kln/Mettm3Kln
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

 MP:0002754 dilated right ventricle "an expansion in the volume of the lower right chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mettm3Kln/Mettm3Kln
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

 MP:0004061 papillary muscle hypoplasia "decreased cell number in the papillary muscle leading to reduced size" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mettm3Kln/Mettm3Kln
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

 MP:0010428 abnormal heart right ventricle outflow tract morphology "any structural anomaly of the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mettm3Kln/Mettm3Kln
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Mettm3Kln/Mettm3Kln
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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