ENSMUSG00000037470


Mus musculus

Features
Gene ID: ENSMUSG00000037470
  
Biological name :Uggt1
  
Synonyms : Q6P5E4 / UDP-glucose glycoprotein glucosyltransferase 1 / Uggt1
  
Possible biological names infered from orthology : Q9NYU2
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: B
Gene start: 36140027
Gene end: 36244720
  
Corresponding Affymetrix probe sets: 10353803 (MoGene1.0st)   1432318_at (Mouse Genome 430 2.0 Array)   1448009_at (Mouse Genome 430 2.0 Array)   1455839_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133971
Ensembl peptide - ENSMUSP00000037930
Ensembl peptide - ENSMUSP00000133929
Ensembl peptide - ENSMUSP00000134078
Ensembl peptide - ENSMUSP00000134640
NCBI entrez gene - 320011     See in Manteia.
MGI - MGI:2443162
RefSeq - XM_006496062
RefSeq - NM_198899
RefSeq Peptide - NP_942602
swissprot - G3UZU8
swissprot - G3UY73
swissprot - G3UY35
swissprot - Q6P5E4
swissprot - G3UYG7
Ensembl - ENSMUSG00000037470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uggt1ENSDARG00000054746Danio rerio
 UGGT1ENSGALG00000002141Gallus gallus
 UGGT1ENSG00000136731Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Uggt2 / UDP-glucose glycoprotein glucosyltransferase 2 / Q9NYU1*ENSMUSG0000004210452


Protein motifs (from Interpro)
Interpro ID Name
 IPR009448  UDP-glucose:Glycoprotein Glucosyltransferase
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0018279 protein N-linked glycosylation via asparagine IBA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IBA
 biological_processGO:0051084 "de novo" posttranslational protein folding IBA
 biological_processGO:0071712 ER-associated misfolded protein catabolic process IBA
 biological_processGO:0097359 UDP-glucosylation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005788 endoplasmic reticulum lumen ISS
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment ISS
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002410 decreased susceptibility to viral infection "reduced likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0009790 decreased susceptibility to viral infection induced morbidity/mortality "reduced likelihood that an organism will display the expected moribund state caused by a viral invasion or from components of or toxins produced by a virus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0020185 altered susceptibility to viral infection "a change in the likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus" [GOC:NV]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0020352 abnormal endoplasmic reticulum physiology "any functional anomaly of the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells" [GO:0005783, ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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